Zantac

Generic Name: ranitidine (ra NI ti deen)
Brand Names: Zantac, Zantac 150, Zantac 300, Zantac 75, Zantac EFFERdose

What is Zantac?

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Zantac is in a group of drugs called histamine-2 blockers. Zantac works by reducing the amount of acid your stomach produces.

Zantac is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Zantac also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

Zantac may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Zantac?

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have kidney disease, liver disease, or porphyria.

Using Zantac may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia.

Zantac granules and effervescent tablets must be dissolved in water before you take them.

Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it. Avoid drinking alcohol. It can increase the risk of damage to your stomach. It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.

What should I discuss with my healthcare provider before using Zantac?

Do not use this medication if you are allergic to ranitidine.

Before using Zantac, tell your doctor if you are allergic to any drugs, or if you have:

kidney disease;
liver disease; or
porphyria.

If you have any of the conditions listed above, you may need a dose adjustment or special tests to safely take Zantac.

The Zantac effervescent tablet may contain phenylalanine. Talk to your doctor before using this form of Zantac if you have phenylketonuria (PKU).

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Zantac passes into breast milk. Do not take Zantac without telling your doctor if you are breast-feeding a baby.

How should I take Zantac?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.

Do not crush, chew, or break the Zantac effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water.

Allow the tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth.

Zantac granules should be mixed with 6 to 8 ounces of water before drinking.

Measure the liquid form of Zantac with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using Zantac.

Store Zantac at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include lack of coordination, feeling light-headed, or fainting.

What should I avoid while taking Zantac?

Avoid drinking alcohol. It can increase the risk of damage to your stomach.

Zantac side effects

Stop using Zantac and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

chest pain, fever, feeling short of breath, coughing up green or yellow mucus;
easy bruising or bleeding, unusual weakness;
fast or slow heart rate;
problems with your vision;
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

headache (may be severe);
drowsiness, dizziness;
sleep problems (insomnia);
decreased sex drive, impotence, or difficulty having an orgasm; or
swollen or tender breasts (in men);
nausea, vomiting, stomach pain; or
diarrhea or constipation.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zantac?

Before taking Zantac, tell your doctor if you are taking triazolam (Halcion). You may not be able to use Zantac, or you may need dosage adjustments or special tests during treatment.

There may be other drugs that can interact with Zantac, or be affected by Zantac. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about Zantac.

What does my medication look like?

Ranitidine is available with a prescription under the brand name Zantac. It is also available over the counter under the brand name Zantac 75. Other brand and generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Zantac 150 mg Tablets - five-sided, peach-colored, film-coated tablets
Zantac 25 mg and 150 mg EFFERdose Tablets - round, white, flat-faced, beveled tablets
Zantac 150 mg EFFERdose Granules - white/pale-yellow granules
Zantac 300 mg Tablets - capsule-shaped, yellow, film-coated tablets
Zantac 300 mg Capsule - beige, soft-gelatin capsules
Zantac Syrup 15 mg/mL - clear, peppermint-flavored liquid

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.