Vospire ER Side Effects
Generic Name: albuterol
Note: This page contains side effects data for the generic drug albuterol. It is possible that some of the dosage forms included below may not apply to the brand name Vospire ER.
It is possible that some side effects of Vospire ER may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to albuterol: oral syrup, oral tablet, oral tablet extended release
Other dosage forms:
As well as its needed effects, albuterol (the active ingredient contained in Vospire ER) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking albuterol, check with your doctor immediately:More common
- Shakiness in the legs, arms, hands, or feet
- trembling or shaking of the hands or feet
- Fast, irregular, pounding, or racing heartbeat or pulse
- difficulty breathing
- difficulty with swallowing
- hives or welts
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- noisy breathing
- redness of the skin
- shortness of breath
- skin rash
- slow or irregular breathing
- swelling of the mouth or throat
- tightness in the chest
- arm, back, or jaw pain
- blurred vision
- chest pain or discomfort
- extra heartbeats
- mood or mental changes
- muscle pain or cramps
- muscle spasm or jerking of all extremities
- pounding in the ears
- sudden loss of consciousness
- total body jerking
- unusual feeling of excitement
Some albuterol side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:Less common
- feeling of warmth
- redness of the face, neck, arms, and occasionally, upper chest
- trouble with holding or releasing urine
- trouble sleeping
- unable to sleep
- unusual drowsiness
- Bad, unusual, or unpleasant (after) taste
- change in taste
- feeling of constant movement of self or surroundings
- rough, scratchy sound to voice
- sensation of spinning
- tightness in the throat
For Healthcare Professionals
Applies to albuterol: compounding powder, inhalation aerosol, inhalation aerosol with adapter, inhalation capsule, inhalation solution, oral syrup, oral tablet, oral tablet extended release
Albuterol is generally well-tolerated and adverse effects seen are consistent with its pharmacological activity. In general, the severity of these adverse effects is dependent on the dose and route of administration. Administration by metered-dose inhaler (MDI) is associated with less systemic effects than administration of higher dosages orally or by nebulizer. Tolerance may develop to the adverse effects of albuterol (the active ingredient contained in Vospire ER)
Changes in heart rate of approximately 20% may be produced by 0.18 mg of albuterol (the active ingredient contained in Vospire ER) by MDI. Aggravation of angina may be due to tachycardia produced by albuterol. Atrial fibrillation was reported in one patient when a spacer device was utilized with an albuterol inhaler, thus increasing the available dose for systemic absorption. Supraventricular ectopic beats and ventricular tachycardia have also been reported. Higher doses of albuterol should be used with caution in patients with cardiac disease, arrhythmias, or hypertension. All of these effects are dose-related and lower doses may be tolerated.
The cardiovascular side effects have included palpitations, peripheral vasodilatation and reflex tachycardia with blood pressure increasing or decreasing. Albuterol in higher dosages has been reported to aggravate angina, myocardial ischemia, or cause atrial or ventricular arrhythmias. Pulmonary edema has been reported in pregnant patients receiving intravenous albuterol. Postmarketing reports have included hypotension.
Musculoskeletal side effects have included tremors, particularly at higher dosages. Tolerance can develop to the tremorogenic effects. Severe muscle cramping may occur infrequently.
Following doses of 15 mg albuterol (the active ingredient contained in Vospire ER) via nebulizer, hyperkalemic patients on hemodialysis experienced a 0.9 mEq/L decrease in plasma potassium which was sustained for 6 hours. Albuterol may stimulate sodium-potassium ATPase, resulting in an intracellular shift of potassium.
Transient lactic acidosis has been reported after administration of inhaled albuterol for an asthma attack.
Metabolic side effects have included hypokalemia, and less commonly, hyperglycemia and lactic acidosis. Postmarketing reports have included metabolic acidosis. Diabetic ketoacidosis has been reported due to overdose of albuterol.
Nervous system side effects have included restlessness, anxiety, nervousness, irritability, and insomnia. Postmarketing reports have included tremor.
Psychiatric side effects have included psychoses presenting as auditory hallucinations and persecutory delusions. These effects are generally associated with higher dosages.
Concern over the development of tachyphylaxis to the bronchodilating effects of albuterol (the active ingredient contained in Vospire ER) has been expressed. Although conflicting data exist, complete tolerance has not been reported.
Respiratory side effects have included paradoxical bronchospasm.
More about Vospire ER (albuterol)
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