Natazia Side Effects
Generic Name: dienogest / estradiol
Note: This document contains side effect information about dienogest / estradiol. Some of the dosage forms listed on this page may not apply to the brand name Natazia.
Some side effects of Natazia may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to dienogest / estradiol: tablets
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking dienogest / estradiol:
Acne; breast tenderness or enlargement; changes in sexual interest; changes in weight; headache; mild fluid retention; nausea; spotting or breakthrough bleeding; stomach cramps or bloating; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); breast discharge; breast discomfort, pain, or lumps; bulging eyes; calf or leg pain, swelling, or tenderness; chest pain; coughing up blood; fainting; mental or mood changes (eg, new or worsening depression); missed menstrual period; new, persistent, or worsening headaches or migraines; persistent or recurrent abnormal vaginal bleeding; persistent or severe dizziness; severe pain or tenderness in the stomach; shortness of breath; swelling of the hands, ankles, or feet; symptoms of heart attack (eg, chest, jaw, or arm pain; sudden, severe nausea or vomiting; shortness of breath; sudden, unusual sweating); symptoms of liver problems (eg, dark urine, pale stools, yellowing of the skin or eyes); symptoms of stroke (eg, one-sided weakness, slurred speech, confusion); unusual vaginal irritation, odor, or discharge; vision loss or other vision changes (eg, double vision).
For Healthcare Professionals
Applies to dienogest / estradiol: oral tablet
Cardiovascular side effects have included venous thromboembolism, cerebrovascular events (thrombotic and hemorrhagic strokes), and myocardial infarctions.
Hepatic side effects have included jaundice, hepatic adenomas, cholestasis, focal nodular hyperplasia of the liver and hepatic carcinoma.
Genitourinary side effects have included irregular uterine bleeding, breast pain, discomfort or tenderness, metrorrhagia and irregular menstruation, uterine leiomyoma, and ruptured ovarian cyst.
Gastrointestinal side effects have included nausea and/or vomiting.
Nervous system side effects have included headache and migraine.
Dermatologic side effects have included acne.
General side effects have included weight gain.
More about Natazia (dienogest / estradiol)
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