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Isovue-128 Side Effects

Generic Name: iopamidol

Note: This page contains information about the side effects of iopamidol. Some of the dosage forms included on this document may not apply to the brand name Isovue-128.

Not all side effects for Isovue-128 may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Applies to iopamidol: injection solution

In addition to its needed effects, some unwanted effects may be caused by iopamidol (the active ingredient contained in Isovue-128). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking iopamidol, check with your doctor or nurse immediately:

Less common
  • Arm, back, or jaw pain
  • blurred vision
  • chest pain or discomfort
  • chest tightness or heaviness
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast or irregular heartbeat
  • feeling of warmth
  • hives
  • lightheadedness, dizziness, or fainting
  • nausea
  • redness of the face, neck, arms, and occasionally, upper chest
  • shortness of breath
  • slow or irregular heartbeat
  • sudden sweating
  • unusual tiredness or weakness
Less common or rare
  • Blue lips and fingernails
  • changes in skin color
  • chills
  • coughing that sometimes produces a pink frothy sputum
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficult, fast, noisy breathing, sometimes with wheezing
  • difficulty in passing urine (dribbling)
  • dizziness
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • headache
  • hives or welts, itching, or skin rash
  • increased sweating
  • nervousness
  • numbness or tingling in the face, arms, or legs
  • pain or discomfort in the arms, jaw, back, or neck
  • pain, tenderness, or swelling of the foot or leg
  • painful urination
  • pale skin
  • pounding in the ears
  • redness of the skin
  • severe, unusual tiredness or weakness
  • trouble speaking, thinking, or walking
  • vomiting
  • Double vision
  • inability to move the arms, legs, or facial muscles
  • pain in the chest, groin, or legs, especially the calves
  • severe, sudden headache
  • slow speech
  • slurred speech
  • sudden loss of coordination
  • sudden, severe weakness or numbness in the arm or leg
  • sudden, unexplained shortness of breath
  • vision changes
Incidence not known
  • Change in consciousness
  • heart stops
  • loss of consciousness
  • no breathing
  • no pulse or blood pressure
  • no sensation in the legs
  • not able to pass urine
  • pain, redness, or pale skin at the injection site
  • seizures
  • unable to move the legs

Some of the side effects that can occur with iopamidol may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common or rare
  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • discouragement
  • disturbed color perception
  • feeling sad or empty
  • halos around lights
  • irritability
  • loss of appetite
  • loss of interest or pleasure
  • loss of vision
  • night blindness
  • overbright appearance of lights
  • stuffy nose
  • trouble concentrating
  • trouble sleeping
  • tunnel vision
  • weight loss
Incidence not known
  • Abdominal or stomach cramps
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • burning, dry, or itching eyes
  • discharge or excessive tearing
  • general feeling of discomfort or illness
  • loss of memory
  • problems with memory
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • runny nose
  • sneezing
  • trembling or shaking of the hands or feet

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.