Farxiga Side Effects

Generic Name: dapagliflozin

Note: This page contains information about the side effects of dapagliflozin. Some of the dosage forms included on this document may not apply to the brand name Farxiga.

Not all side effects for Farxiga may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to dapagliflozin: oral tablet

In addition to its needed effects, some unwanted effects may be caused by dapagliflozin (the active ingredient contained in Farxiga). In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking dapagliflozin:

More common
  • Anxiety
  • bladder pain
  • bloody or cloudy urine
  • blurred vision
  • chills
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • decreased frequency or amount of urine
  • depression
  • difficult, burning, or painful urination
  • dizziness
  • fast heartbeat
  • frequent urge to urinate
  • headache
  • increased hunger
  • increased thirst
  • itching of the vagina or genitals
  • loss of appetite
  • lower back or side pain
  • nausea
  • nightmares
  • seizures
  • shakiness
  • slurred speech
  • swelling of the face, fingers, or lower legs
  • thick, white vaginal discharge with mild or no odor
  • troubled breathing
  • unusual tiredness or weakness
  • vomiting
  • weight gain
Less common
  • Foul smelling discharge from the penis
  • pain in the skin around the penis
  • rash of the penis
  • redness, itching, or swelling of the penis
  • Cough
  • difficulty with swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • fainting
  • increase in heart rate
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • lightheadedness
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid breathing
  • skin rash, hives, or itching
  • sunken eyes
  • sweating
  • tightness in the chest
  • wrinkled skin

Some of the side effects that can occur with dapagliflozin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Fever
  • muscle aches
  • sore throat
  • stuffy or runny nose
Less common
  • Back pain
  • difficulty having a bowel movement (stool)
  • pain in the arms or legs

For Healthcare Professionals

Applies to dapagliflozin: oral tablet


Frequency not reported: Dapagliflozin (the active ingredient contained in Farxiga) causes an osmotic diuresis, which may lead to reductions in intravascular volume. Adverse reactions related to volume depletion (dehydration, hypovolemia, orthostatic hypotension, or hypotension) have been reported. The frequency of these side effects vary widely according to patient age, renal status, dose being taken, time on therapy, and concomitant drug therapy.


Common (1% to 10%): Nausea, constipation


Common (1% to 10%):
-Genital mycotic infections (MALES: Balanitis, fungal genital infection, balanitis candida, genital candidiasis, genital infection male, penile infection, balanoposthitis, balanoposthitis infective, genital infection, posthitis; FEMALES: Vulvovaginal mycotic infection, vaginal infection, vulvovaginal candidiasis, vulvovaginitis, genital infection, genital candidiasis, fungal genital infection, vulvitis, genitourinary tract infection, vulval abscess, and vaginitis bacterial)
-Urinary tract infections (urinary tract infection, cystitis, Escherichia urinary tract infection, genitourinary tract infection, pyelonephritis, trigonitis, urethritis, kidney infection, and prostatitis)
-Increased urination (pollakiuria, polyuria, and urine output increased)
-Discomfort with urination


Uncommon (0.1% to 1%): Anaphylactic reactions, cutaneous adverse reactions, angioedema
Frequency not reported: Angioedema, urticaria, hypersensitivity


Common (1% to 10%): Influenza


Common (1% to 10%): Dyslipidemia, volume depletion (including dehydration, hypovolemia, orthostatic hypotension, or hypotension)
Frequency not reported: Hypoglycemia with concomitant use with insulin and insulin secretagogues, increases in low-density lipoprotein cholesterol (LDL-C)


Very rare (less than 0.01%): Bladder cancer


Frequency not reported: Impairment in renal function, increases in serum creatinine, decreases in estimated glomerular filtration rate (eGFR)


Common (1% to 10%): Nasopharyngitis

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