Farxiga Side Effects

Generic Name: dapagliflozin

Note: This page contains information about the side effects of dapagliflozin. Some of the dosage forms included on this document may not apply to the brand name Farxiga.

Not all side effects for Farxiga may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to dapagliflozin: oral tablet

Along with its needed effects, dapagliflozin (the active ingredient contained in Farxiga) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dapagliflozin:

More common
  • Anxiety
  • bladder pain
  • bloody or cloudy urine
  • blurred vision
  • chills
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • decreased frequency or amount of urine
  • depression
  • difficult, burning, or painful urination
  • dizziness
  • fast heartbeat
  • frequent urge to urinate
  • headache
  • increased hunger
  • increased thirst
  • itching of the vagina or genitals
  • loss of appetite
  • lower back or side pain
  • nausea
  • nightmares
  • seizures
  • shakiness
  • slurred speech
  • swelling of the face, fingers, or lower legs
  • thick, white vaginal discharge with mild or no odor
  • troubled breathing
  • unusual tiredness or weakness
  • vomiting
  • weight gain
Less common
  • Foul smelling discharge from the penis
  • pain in the skin around the penis
  • rash of the penis
  • redness, itching, or swelling of the penis
Rare
  • Cough
  • difficulty with swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • fainting
  • increase in heart rate
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • lightheadedness
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid breathing
  • skin rash, hives, or itching
  • sunken eyes
  • sweating
  • tightness in the chest
  • wrinkled skin

Some side effects of dapagliflozin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Fever
  • muscle aches
  • sore throat
  • stuffy or runny nose
Less common
  • Back pain
  • difficulty having a bowel movement (stool)
  • pain in the arms or legs

For Healthcare Professionals

Applies to dapagliflozin: oral tablet

Cardiovascular

Frequency not reported: Dapagliflozin (the active ingredient contained in Farxiga) causes an osmotic diuresis, which may lead to reductions in intravascular volume. Adverse reactions related to volume depletion (dehydration, hypovolemia, orthostatic hypotension, or hypotension) have been reported. The frequency of these side effects vary widely according to patient age, renal status, dose being taken, time on therapy, and concomitant drug therapy.

Gastrointestinal

Common (1% to 10%): Nausea, constipation

Genitourinary

Common (1% to 10%):
-Genital mycotic infections (MALES: Balanitis, fungal genital infection, balanitis candida, genital candidiasis, genital infection male, penile infection, balanoposthitis, balanoposthitis infective, genital infection, posthitis; FEMALES: Vulvovaginal mycotic infection, vaginal infection, vulvovaginal candidiasis, vulvovaginitis, genital infection, genital candidiasis, fungal genital infection, vulvitis, genitourinary tract infection, vulval abscess, and vaginitis bacterial)
-Urinary tract infections (urinary tract infection, cystitis, Escherichia urinary tract infection, genitourinary tract infection, pyelonephritis, trigonitis, urethritis, kidney infection, and prostatitis)
-Increased urination (pollakiuria, polyuria, and urine output increased)
-Discomfort with urination

Hypersensitivity

Uncommon (0.1% to 1%): Anaphylactic reactions, cutaneous adverse reactions, angioedema
Frequency not reported: Angioedema, urticaria, hypersensitivity

Immunologic

Common (1% to 10%): Influenza

Metabolic

Common (1% to 10%): Dyslipidemia, volume depletion (including dehydration, hypovolemia, orthostatic hypotension, or hypotension)
Frequency not reported: Hypoglycemia with concomitant use with insulin and insulin secretagogues, increases in low-density lipoprotein cholesterol (LDL-C)

Oncologic

Very rare (less than 0.01%): Bladder cancer

Renal

Frequency not reported: Impairment in renal function, increases in serum creatinine, decreases in estimated glomerular filtration rate (eGFR)

Respiratory

Common (1% to 10%): Nasopharyngitis

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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