SGLT-2 inhibitors
Other names: SGLT2 inhibitors, sodium-glucose cotransporter-2 inhibitors
What are SGLT-2 inhibitors?
SGLT-2 inhibitor is an abbreviation for sodium-glucose cotransporter-2 inhibitors. SGLT-2 inhibitors are a class of medicine used to lower high blood glucose levels in people with type 2 diabetes. They may also be called gliflozins.
SGLT-2 inhibitors inhibit SGLT-2 proteins located in the renal tubules of the kidneys which are responsible for reabsorbing glucose back into the blood. As a result, more glucose is excreted in the urine. SGLT-2 inhibitors have been shown to be effective at lowering hemoglobin A1c levels, improving weight loss and lowering blood pressure. They carry a low risk of hypoglycemia (low blood sugar levels).
They are usually well tolerated. SGLT-2 inhibitors may be used in the treatment of type 2 diabetes and act independently of beta-cell function in the pancreas.
List of SGLT-2 inhibitors
| Drug Name | Avg. Rating | Reviews |
|---|---|---|
| empagliflozin systemic (Pro) Brand name: Jardiance |
348 reviews | |
| canagliflozin systemic (Pro) Brand name: Invokana |
265 reviews | |
| dapagliflozin systemic (Pro) Brand name: Farxiga |
199 reviews | |
| ertugliflozin systemic (Pro) Brand name: Steglatro |
13 reviews | |
| bexagliflozin systemic (Pro) Brand name: Brenzavvy |
1 review | |
| sotagliflozin systemic (Pro) Brand name: Inpefa | No reviews | |
| For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). | ||
See also
Medical conditions treated or associated with SGLT-2 inhibitors:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.