Farxiga Dosage
Generic name: DAPAGLIFLOZIN PROPANEDIOL 5mg
Dosage form: tablet, film coated
Drug class: SGLT-2 inhibitors
Medically reviewed by Drugs.com. Last updated on Jan 15, 2024.
Prior to Initiation of FARXIGA
Assess renal function prior to initiation of FARXIGA therapy and then as clinically indicated [see Warnings and Precautions (5.2)].
Assess volume status. In patients with volume depletion, correct this condition before initiating FARXIGA [see Warnings and Precautions (5.2) and Use in Specific Populations (8.5, 8.6)].
Recommended Dosage
See Table 1 for dosage recommendations based on estimated glomerular filtration rate (eGFR).
|
|
eGFR |
Recommended Dose |
eGFR 45 or greater |
To improve glycemic control, the recommended starting dose is 5 mg orally once daily. Dose can be increased to 10 mg orally once daily for additional glycemic control*. For all other indications, the recommended starting dose is 10 mg orally once daily. |
eGFR 25 to less than 45 |
10 mg orally once daily*. |
eGFR less than 25 |
Initiation is not recommended; however, patients may continue 10 mg orally once daily to reduce the risk of eGFR decline, ESKD, CV death and hHF. |
hHF: hospitalization for heart failure, CV: Cardiovascular, ESKD: End Stage Kidney Disease. |
2.3 Temporary Interruption for Surgery
Withhold FARXIGA for at least 3 days, if possible, prior to major surgery or procedures associated with prolonged fasting. Resume FARXIGA when the patient is clinically stable and has resumed oral intake [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.2)].
Frequently asked questions
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