Skip to Content

Generic Name: insulin aspart (IN su lin AS part)
Brand Names: NovoLOG, NovoLOG FlexPen, NovoLOG PenFill

What is NovoLog?

NovoLog (insulin aspart) is a fast-acting form of insulin that works by lowering levels of glucose (sugar) in the blood.

NovoLog is used to improve blood sugar control in adults and children who are at least 2 years old who have type 1 (insulin-dependent) diabetes.

NovoLog is usually given together with an intermediate or long-acting insulin.

Important information

NovoLog is a fast-acting insulin that begins to work very quickly. After using it, you should eat a meal within 5 to 10 minutes.

Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.

You should not use NovoLog if you are having an episode of hypoglycemia (low blood sugar).

Before taking this medicine

You should not use NovoLog if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).

To make sure NovoLog is safe for you, tell your doctor if you have:

  • liver or kidney disease; or

  • if you take any oral (taken by mouth) diabetes medicine.

NovoLog is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether insulin aspart passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

NovoLog is not approved for use by anyone younger than 2 years old. This medicine is not for use in children with type 2 diabetes.

How should I use NovoLog?

Use NovoLog exactly as it was prescribed for you. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

NovoLog is given as an injection (shot) under your skin, using a needle and syringe or an insulin pump. You will be shown how to use injections at home. Do not self inject this medicine if you do not understand how to give the injection and properly dispose of used needles and syringes.

NovoLog is a fast-acting medicine that begins to work very quickly. After using NovoLog, you should eat a meal within 5 to 10 minutes.

Choose a different place in your injection skin area each time you use this medication. Do not inject into the same place two times in a row.

If you use this medicine with an insulin pump, do not mix or dilute NovoLog with any other insulin. Infusion pump tubing, catheters, and the needle location on your skin should be changed every 3 days. Change the medicine in the reservoir every 6 days.

Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.

Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, hard candy, crackers, raisins, and non-diet soda. Be sure your family and close friends know how to help you in an emergency.

If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice.

NovoLog is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Do not freeze insulin or expose it to high heat or bright light. Do not use any insulin that has been frozen or has been in temperatures above 98 degrees F.

Storing unopened NovoLog in a refrigerator: Store in the original carton and do not freeze. Throw away unopened insulin if the expiration date on the label has passed.

Storing unopened NovoLog at room temperature: Store in the original carton. Throw away unopened insulin if not used within 28 days.

Storing "in-use" vials: After first use, store the vial in a refrigerator or at room temperature. Use within 28 days.

Storing "in-use" cartridges or injection pens: After first use, store the cartridge or pen at room temperature. Do not refrigerate. Use within 28 days.

See also: Dosage Information (in more detail)

What happens if I miss a dose?

Since NovoLog is used before meals, you may not be on a timed dosing schedule. Whenever you use this medicine, be sure to eat a meal within 5 to 10 minutes. Do not use extra to make up a missed dose.

It is important to keep NovoLog on hand at all times. Get your prescription refilled before you run out of medicine completely.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An insulin overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, seizure (convulsions), or coma.

What should I avoid while using NovoLog?

Do not change the brand of insulin aspart or syringe you are using without first talking to your doctor or pharmacist.

Avoid drinking alcohol. It can lower your blood sugar while using NovoLog.

NovoLog side effects

Get emergency medical help if you have any signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out.

Call your doctor if you have a serious side effect such as:

  • swelling in your hands or feet; or

  • low potassium--confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling.

Common NovoLog side effects may include low blood sugar (headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect NovoLog?

Many other medicines can increase or decrease the effects of NovoLog on lowering your blood sugar. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about NovoLog.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use NovoLog only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 5.04. Revision Date: 2016-05-11, 3:33:10 PM.

Hide