Medication Guide App

Atrovent Side Effects

Generic Name: ipratropium

Note: This page contains information about the side effects of ipratropium. Some of the dosage forms included on this document may not apply to the brand name Atrovent.

Not all side effects for Atrovent may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to ipratropium: inhalation aerosol powder, inhalation solution

In addition to its needed effects, some unwanted effects may be caused by ipratropium (the active ingredient contained in Atrovent). In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking ipratropium:

More common
  • Bladder pain
  • bloody or cloudy urine
  • cough producing mucus
  • difficult, burning, or painful urination
  • difficulty with breathing
  • frequent urge to urinate
  • lower back or side pain
  • shortness of breath
  • tightness in the chest
  • wheezing
Less common
  • Body aches or pain
  • chills
  • cough
  • ear congestion
  • fever
  • headache
  • loss of voice
  • runny nose
  • sneezing
  • sore throat
  • unusual tiredness or weakness
  • Constipation (continuing) or lower abdominal pain or bloating
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • severe eye pain
  • skin rash or hives
  • swelling of the face, lips, or eyelids
Incidence not known
  • Blindness
  • blurred vision
  • confusion
  • decrease in the frequency of urination
  • decrease in the urine volume
  • decreased vision
  • difficulty in passing urine (dribbling)
  • difficulty with swallowing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • hives or welts
  • itching
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • nausea or vomiting
  • noisy breathing
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • redness of the white part of the eyes or inside of the eyelids
  • sweating
  • tearing

Some of the side effects that can occur with ipratropium may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Back pain
  • dryness of the mouth
  • unpleasant taste
Less common or rare
  • Acid or sour stomach
  • belching
  • burning eyes
  • diarrhea
  • general feeling of discomfort or illness
  • heartburn
  • indigestion
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • nervousness
  • pain or tenderness around the eyes and cheekbones
  • shivering
  • stomach discomfort, upset, or pain
  • trembling
  • trouble sleeping

For Healthcare Professionals

Applies to ipratropium: compounding powder, inhalation aerosol, inhalation solution


Most common adverse reactions were bronchitis, COPD exacerbation, dyspnea, headache

Nervous system

Common (1% to 10%): Headache, dizziness


Postmarketing reports: Skin rash, pruritus, angioedema (including that of tongue, lips and face), urticarial (including giant urticaria), laryngospasm and anaphylactic reactions


Frequency not reported: Precipitation or worsening of narrow-angle glaucoma, glaucoma, halo vision, conjunctival hyperemia, corneal edema, acute eye pain, blurred vision
Postmarketing reports: Mydriasis, increased intraocular pressure


Common (1% to 10%): Urinary tract infection
Postmarketing reports: Urinary retention


Very common (10% or more): Bronchitis, COPD exacerbation, sinusitis
Common (1% to 10%): Dyspnea, sinusitis, cough, rhinitis, upper respiratory infection
Postmarketing reports: Cough, bronchospasm (including paradoxical bronchospasm)


Frequency not reported: Hypotension, palpitations, tachycardia
Postmarketing reports: Supraventricular tachycardia, atrial fibrillation, increased heart rate


Common (1% to 10%): Dyspepsia, dry mouth, nausea
Uncommon (0.1% to 1%): Taste perversion (bitter taste)
Frequency not reported: Dry throat, constipation, throat irritation, stomatitis, mouth edema
Postmarketing reports: Gastrointestinal distress (diarrhea, nausea, vomiting), pharyngeal edema, gastrointestinal motility disorders


Common (1% to 10%): Back pain


Common (1% to 10%): Influenza-like symptoms
Postmarketing reports: Accommodation disorder

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