Calcium channel blocking agents
A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Calcium channel blockers block voltage gated calcium channels and inhibits the influx of calcium ions into cardiac and smooth muscle cells. The decrease in intracellular calcium reduces the strength of heart muscle contraction, reduces conduction of impulses in the heart, and causes vasodilatation.
Decrease in intracellular calcium in the heart decreases cardiac contractility. Decreased calcium in the vascular smooth muscle reduces its contraction and therefore causes vasodilatation.
Decrease in cardiac contractility decreases cardiac output and vasodilatation decreases total peripheral resistance, both of which cause a drop in blood pressure.
Calcium channel blocking agents are used to treat hypertension.
Drug Name  ( View by: Brand | Generic )
|
Reviews | Avg. Ratings |
|
|---|---|---|---|
| nimodipine systemic (Pro, More...) |
2 Review(s) | Rate It! | 10 |
| diltiazem systemic (Pro, More...) |
33 Review(s) | Rate It! | 8.0 |
| verapamil systemic (Pro, More...) |
30 Review(s) | Rate It! | 7.8 |
| nifedipine systemic (Pro, More...) |
22 Review(s) | Rate It! | 6.8 |
| amlodipine systemic (Pro, More...) |
76 Review(s) | Rate It! | 6.1 |
| felodipine systemic (Pro, More...) |
4 Review(s) | Rate It! | 5.4 |
| isradipine systemic (Pro, More...) |
1 Review(s) | Rate It! | 5.0 |
| bepridil systemic (More...) |
0 Review(s) | Rate It! | 0.0 |
| clevidipine systemic (Pro, More...) |
0 Review(s) | Rate It! | 0.0 |
| nicardipine systemic (Pro, More...) |
0 Review(s) | Rate It! | 0.0 |
| nisoldipine systemic (Pro, More...) |
1 Review(s) | Rate It! | 0.0 |
See also
Medical conditions associated with calcium channel blocking agents:
- Angina
- Angina Pectoris Prophylaxis
- Arrhythmia
- Atrial Fibrillation
- Atrial Flutter
- Bipolar Disorder
- Cluster Headaches
- Coronary Artery Disease
- Heart Failure
- High Blood Pressure
- Hypertensive Emergency
- Hypertrophic Cardiomyopathy
- Idiopathic Hypertrophic Subaortic Stenosis
- Ischemic Stroke
- Migraine Prevention
- Nocturnal Leg Cramps
- Premature Labor
- Raynaud's Syndrome
- Subarachnoid Hemorrhage
- Supraventricular Tachycardia
