Zomig Nasal Spray Dosage
Generic name: zolmitriptan
Dosage form: nasal spray, metered
This dosage information does not include all the information needed to use Zomig Nasal Spray safely and effectively. See full prescribing information for Zomig Nasal Spray.
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Acute Treatment of Migraine Attacks
Administer one dose of ZOMIG Nasal Spray 5 mg for the treatment of acute migraine. If the headache returns, the dose may be repeated after 2 hours. The effectiveness of a second dose has not been established in placebo-controlled trials. The maximum daily dose should not exceed 10 mg in any 24-hour period.
In controlled clinical trials, single doses of 5 mg of zolmitriptan nasal spray were administered into one nostril and were effective for the treatment of acute migraines in adults.
Individuals may vary in response to ZOMIG Nasal Spray. The pharmacokinetics of a 5 mg nasal spray dose is similar to the 5 mg oral formulations. Doses lower than 5 mg can only be achieved through the use of an oral formulation. The choice of dose, and route of administration should therefore be made on an individual basis.
The safety of treating an average of more than four headaches in a 30-day period has not been established.
Patients with moderate to severe hepatic impairment have decreased clearance of zolmitriptan and significant elevation in blood pressure was observed in some patients. Use of doses less than 2.5 mg of an alternate formulation with blood pressure monitoring is recommended [see Clinical Pharmacology (12.3)andWarnings and Precautions (5.6)].