Methenamine Alternatives Compared
Methenamine | Nitrofurantoin | Macrobid |
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Methenamine | Nitrofurantoin | Macrobid (nitrofurantoin) |
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Prescription and OTC
Prescribed for Prevention of Bladder infection, Urinary Tract Infection, Kidney Infections, Bladder Infection. methenamine may also be used for purposes not listed in this medication guide. |
Prescription only
Nitrofurantoin is an effective antibiotic with a low risk of inducing bacterial resistance that is used specifically to treat urinary tract infections caused by susceptible bacteria. Long-term use... View more |
Prescription only
Prescribed for Urinary Tract Infection, Prevention of Bladder infection, Bladder Infection. Macrobid may also be used for purposes not listed in this medication guide. |
Related suggestions Urinary Tract Infection
Bladder Infection
Prevention of Bladder infection (Cystitis Prophylaxis)
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More about Methenamine | More about Nitrofurantoin | More about Macrobid (nitrofurantoin) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Methenamine has an average rating of 8.3 out of 10 from a total of 99 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 13% reported a negative effect. |
Nitrofurantoin has an average rating of 4.4 out of 10 from a total of 1845 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 52% reported a negative effect. |
Macrobid has an average rating of 4.6 out of 10 from a total of 818 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 51% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: methenamine side effects in more detail. |
See also: nitrofurantoin side effects in more detail. |
See also: Macrobid side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all methenamine prices |
View all nitrofurantoin prices |
View all Macrobid prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Hiprex | Furadantin, Macrobid, Macrodantin | Other nitrofurantoin brands include: Furadantin, Macrodantin | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
6 hours |
1 hour |
1 hour |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 49 drugs are known to interact with methenamine:
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A total of 193 drugs are known to interact with nitrofurantoin:
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A total of 193 drugs are known to interact with Macrobid:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
July 05, 1967 |
February 06, 1953 |
December 24, 1991 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.