Methenamine Dosage
This dosage information may not include all the information needed to use Methenamine safely and effectively. See additional information for Methenamine.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Cystitis Prophylaxis
Hippurate: 1 g orally twice a day
Mandelate: 1 g orally every 6 hours
Usual Adult Dose for Cystitis
Hippurate: 1 g orally twice a day for 5 to 7 days
Mandelate: 1 g orally every 6 hours for 5 to 7 days
Usual Pediatric Dose for Cystitis Prophylaxis
6 to 12 years:
Hippurate: 0.5 to 1 g orally twice a day
13 years or older:
Hippurate: 1 g orally twice a day
Mandelate: 1 g orally every 6 hours
Usual Pediatric Dose for Cystitis
6 to 12 years:
Hippurate: 0.5 to 1 g orally twice a day
Mandelate: 0.5 g orally 4 times a day
13 years or older:
Hippurate: 1 g orally twice a day for 5 to 7 days
Mandelate: 1 g orally every 6 hours for 5 to 7 days
Renal Dose Adjustments
CrCl less than 10 mL/min: Methenamine is contraindicated in patients with severe renal insufficiency due to the risk of systemic acidosis.
Liver Dose Adjustments
No adjustment recommended.
Precautions
Use with caution in patients with liver disease or renal dysfunction due to the risk of systemic acidosis.
Dialysis
Patients on dialysis should not receive methenamine due to the risk of systemic acidosis.
Other Comments
Methenamine should be taken with food, drink plenty of liquids, and avoid alkalizing agents, including copious amounts of antacids.
Methenamine is generally not used for treatment of active urinary tract infections.
