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Nitrofurantoin Dosage

Medically reviewed by Drugs.com. Last updated on Feb 14, 2024.

Applies to the following strengths: macrocrystals 50 mg; macrocrystals 100 mg; macrocrystals 25 mg; macrocrystals-monohydrate 100 mg; 25 mg/5 mL; 50 mg/5 mL; macrocrystals

Usual Adult Dose for Cystitis

Capsules (macrocrystals) and oral suspension: 50 to 100 mg orally 4 times a day
Dual-release capsules (macrocrystals-monohydrate): 100 mg orally every 12 hours

Duration of Therapy:


Comments:

Uses:

Usual Adult Dose for Urinary Tract Infection

Capsules (macrocrystals) and oral suspension: 50 to 100 mg orally 4 times a day
Dual-release capsules (macrocrystals-monohydrate): 100 mg orally every 12 hours

Duration of Therapy:


Comments:

Uses:

Usual Adult Dose for Cystitis Prophylaxis

Capsules (macrocrystals) and oral suspension: Reducing dose to 50 to 100 mg orally once a day at bedtime may be adequate.

Comments:


Use: For long-term suppressive therapy

Usual Pediatric Dose for Cystitis

Capsules (Macrocrystals) and Oral Suspension:
1 month or older: 5 to 7 mg/kg/day orally in 4 divided doses


Fixed dosing recommendations (oral suspension):

Dual-Release Capsules (Macrocrystals-Monohydrate):
12 years or older: 100 mg orally every 12 hours

Duration of Therapy:

Comments:

Uses:

Usual Pediatric Dose for Urinary Tract Infection

Capsules (Macrocrystals) and Oral Suspension:
1 month or older: 5 to 7 mg/kg/day orally in 4 divided doses


Fixed dosing recommendations (oral suspension):

Dual-Release Capsules (Macrocrystals-Monohydrate):
12 years or older: 100 mg orally every 12 hours

Duration of Therapy:

Comments:

Uses:

Usual Pediatric Dose for Cystitis Prophylaxis

Capsules (Macrocrystals) and Oral Suspension:
1 month or older: Doses as low as 1 mg/kg/day orally in 1 or 2 divided doses may be adequate.


Comments:

Use: For long-term suppressive therapy

Renal Dose Adjustments

Anuria, oliguria, or significant renal dysfunction (CrCl less than 60 mL/min or significantly elevated creatinine): Contraindicated

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:


Capsules (macrocrystals) and oral suspension: Safety and efficacy have not been established in patients younger than 1 month.
Dual-release capsules (macrocrystals-monohydrate): Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

This drug is dialyzable; however, no dose adjustment guidelines have been reported.

Other Comments

Administration advice:


Storage requirements:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.