Butorphanol solution

Pronunciation

Generic Name: butorphanol (bue-TOR-fa-nol)
Brand Name: Generic only. No brands available.

Butorphanol solution is used for:

Relieving headache or pain due to surgery or other causes. It may also be used for other conditions as determined by your doctor.

Butorphanol solution is a narcotic analgesic. It works in certain areas of the brain and nervous system to decrease pain.

Do NOT use butorphanol solution if:

  • you are allergic to any ingredient in butorphanol solution, including the preservative benzethonium chloride
  • you drink alcohol
  • you are dependent on narcotic pain relievers
  • you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using butorphanol solution:

Some medical conditions may interact with butorphanol solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had an allergic reaction to any narcotic pain reliever (eg, oxycodone, dihydrocodeine, hydromorphone)
  • if you have stomach or bowel problems (eg, inflammatory bowel disease); prostate problems; asthma or other lung or breathing problems; heart problems (eg, cor pulmonale, heart blood vessel problems, heart failure); liver or kidney disease; high or low blood pressure; an underactive thyroid; seizures; or urinary problems
  • if you have severe drowsiness, or have or have recently had increased pressure in the brain, an unusual growth in the brain (eg, tumor), a recent head injury, or an infection of the brain or nervous system
  • if you have a certain bowel problem (pseudomembranous colitis) or stomach pain, or have recently had a heart attack, stomach or bowel surgery, or an injury
  • if you have developed low blood pressure from taking other narcotic pain relievers (eg, morphine)
  • if you have a history drug or alcohol abuse or dependence, or suicidal thoughts or behaviors

Some MEDICINES MAY INTERACT with butorphanol solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Nasal decongestants (eg, oxymetazoline) because they may delay the time it takes for butorphanol solution to work
  • Cimetidine because it may increase the risk of butorphanol solution's side effects
  • Naltrexone or rifamycins (eg, rifampin) because they may decrease butorphanol solution's effectiveness
  • Sodium oxybate (GHB) because the risk of its side effects may be increased by butorphanol solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if butorphanol solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use butorphanol solution:

Use butorphanol solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Butorphanol solution comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get butorphanol solution refilled.
  • Butorphanol solution is supplied as a nasal pump. Your pharmacist will assemble the pump for you. Contact your pharmacist if you have any questions.
  • For instructions on the proper use of butorphanol solution, read the extra patient leaflet that is available with butorphanol solution. Talk to your pharmacist if you have questions about this information.
  • Prime the pump before the first use and any time it has not been used within 48 hours or longer. When priming, aim the pump away from yourself, other people, and animals.
  • The usual dose of butorphanol solution is 1 spray into 1 nostril. Do not spray into both nostrils unless directed by your doctor.
  • When not in use, store butorphanol solution in the child-resistant plastic container.
  • Tell your doctor if your pain has not improved after using butorphanol solution or if it becomes worse.
  • If you also use sumatriptan nasal spray, ask your doctor or pharmacist how to use it if you need to use butorphanol solution as well.
  • If you miss a dose of butorphanol solution and are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use butorphanol solution.

Important safety information:

  • Butorphanol solution may cause drowsiness or dizziness. These effects usually occur within the first hour after taking a dose, though they may be persist for longer periods of time. These effects may be worse if you take it with alcohol or certain medicines. Use butorphanol solution with caution. Do not drive or perform other possibly unsafe tasks for at least 1 hour after taking a dose until you know how you react to it.
  • Do not drink alcohol while you are using butorphanol solution.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using butorphanol solution; it may add to their effects. Ask your pharmacist about which medicines may cause drowsiness.
  • Tell your doctor or dentist that you take butorphanol solution before you receive any medical or dental care, emergency care, or surgery.
  • Do NOT take more than the recommended dose, use more often than prescribed, or use for longer than prescribed without checking with your doctor.
  • Use butorphanol solution with caution in the ELDERLY; they may be more sensitive to its effects, including constipation, dizziness, drowsiness, headache, light-headedness, nausea, stuffy nose, and vomiting.
  • Butorphanol solution should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using butorphanol solution while you are pregnant. Butorphanol solution is found in breast milk. If you are or will be breast-feeding while you use butorphanol solution, check with your doctor. Discuss any possible risks to your baby.

Some people who use butorphanol solution for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking butorphanol solution suddenly, you may have WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of butorphanol solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth; light-headedness; nasal irritation; nausea; runny nose; sore throat; stuffy nose; trouble sleeping; unpleasant taste; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; burning, numbness, or tingling; change in the amount of urine produced; chest pain; confusion; ear pain; fainting; fast, slow, or irregular heartbeat; flushing; hallucinations; mental or mood changes (eg, agitation, anxiety, depression); restlessness; ringing in the ears; seizures; severe or persistent dizziness, drowsiness, or light-headedness; severe or persistent headache or trouble sleeping; shortness of breath; slow, shallow, or difficult breathing; tremors; unusual swelling.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include cold and clammy skin; deep sleep; loss of consciousness; seizures; severe drowsiness, dizziness, or light-headedness; slow, shallow, or difficult breathing; slow heartbeat.

Proper storage of butorphanol solution:

Store butorphanol solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep butorphanol solution out of the reach of children and away from pets.

General information:

  • If you have any questions about butorphanol solution, please talk with your doctor, pharmacist, or other health care provider.
  • Butorphanol solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take butorphanol solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about butorphanol solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to butorphanol solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using butorphanol solution.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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