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Zirgan Side Effects

Generic Name: ganciclovir ophthalmic

Note: This page contains side effects data for the generic drug ganciclovir ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name Zirgan.

For the Consumer

Applies to ganciclovir ophthalmic: intraocular implant

Other dosage forms:

As well as its needed effects, ganciclovir ophthalmic (the active ingredient contained in Zirgan) may cause unwanted side effects that require medical attention.

Also, ganciclovir has been found to cause cancerous tumors in animals. Discuss these possible effects with your doctor.

Severity: Moderate

If any of the following side effects occur while taking ganciclovir ophthalmic, check with your doctor or nurse as soon as possible:

More common—Usually occur within the first 2 months after the surgery
  • Decrease in vision (severe)
  • seeing flashes or sparks of light
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
Less common—Usually occur within the first 2 months after the surgery
  • Blurred vision or other change in vision
  • decreased vision or other change in vision
  • eye pain or tearing
  • red or bloodshot eye
  • sensitivity of eye to light
Rare—Usually occur within the first 2 months after the surgery
  • Eye irritation
  • swelling of the membrane covering the white part of the eye

Minor Side Effects

Some ganciclovir ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Decrease in vision lasting approximately 2 to 4 weeks

For Healthcare Professionals

Applies to ganciclovir ophthalmic: intraocular implant, ophthalmic gel

General

The following side effects are for the ophthalmic gel only; if available, the manufacturer product information for the intraocular implant should be consulted for additional information.

Ocular

Very common (10% or more): Blurred vision (60%), eye irritation (20%), transient burning/stinging sensations
Common (1% to 10%): Punctate keratitis, conjunctival hyperemia[Ref]

References

1. "Product Information. Zirgan (ganciclovir ophthalmic)." Sirion Therapeutics, Tampa, FL.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

It is possible that some side effects of Zirgan may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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