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Zegalogue Side Effects

Generic name: dasiglucagon

Medically reviewed by Last updated on Oct 1, 2022.

Note: This document contains side effect information about dasiglucagon. Some dosage forms listed on this page may not apply to the brand name Zegalogue.

Applies to dasiglucagon: subcutaneous solution.

Serious side effects of Zegalogue

Along with its needed effects, dasiglucagon (the active ingredient contained in Zegalogue) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dasiglucagon:

Incidence not known

  • Blurred vision
  • chest pain, discomfort, or tightness
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, irregular, pounding, or racing heartbeat or pulse
  • headache
  • itching, skin rash
  • lightheadedness, dizziness, or fainting
  • loss of consciousness
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
  • swelling of the eyes or eyelids
  • sweating
  • trouble breathing
  • unusual tiredness or weakness

Other side effects of Zegalogue

Some side effects of dasiglucagon may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • diarrhea
  • nausea
  • vomiting

For Healthcare Professionals

Applies to dasiglucagon: subcutaneous solution.


The most commonly reported adverse reactions have included nausea, vomiting, headache, and injection site pain.[Ref]


Very common (10% or more): Nausea (57%), vomiting (25%)

Common (1% to 10%): Diarrhea


Common (1% to 10%): Injection site pain


Frequency not reported: Hypertension, hypotension, bradycardia, presyncope, palpitations, orthostatic intolerance

Nervous system

Very common (10% or more): Headache (11%)

Frequently asked questions


1. "Product Information. Zegalogue Prefilled Syringe (dasiglucagon)." Zealand Pharma A/S (2021):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.