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Xacduro Side Effects

Generic name: durlobactam / sulbactam

Medically reviewed by Drugs.com. Last updated on Jun 23, 2024.

Note: This document provides detailed information about Xacduro Side Effects associated with durlobactam / sulbactam. Some dosage forms listed on this page may not apply specifically to the brand name Xacduro.

Applies to durlobactam / sulbactam: intravenous powder for solution.

Serious side effects of Xacduro

Along with its needed effects, durlobactam / sulbactam may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking durlobactam / sulbactam:

More common side effects

  • agitation
  • black, tarry stools
  • bleeding gums
  • blood in the urine or stools
  • coma
  • confusion
  • dark urine
  • decreased urine
  • depression
  • dizziness
  • dry mouth
  • diarrhea
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • headache
  • hostility
  • increased thirst
  • irregular heartbeat
  • irritability
  • lethargy
  • loss of appetite
  • mood changes
  • muscle pain, cramps, or twitching
  • nausea or vomiting
  • numbness or tingling in the hands, feet, or lips
  • pale skin
  • pinpoint red spots on the skin
  • rapid weight gain
  • seizures
  • stomach pain
  • stupor
  • swelling of the face, ankles, or hands
  • trouble breathing
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • yellow eyes or skin

Incidence not known

Other side effects of Xacduro

Some side effects of durlobactam / sulbactam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • constipation

For healthcare professionals

Applies to durlobactam / sulbactam: intravenous powder for reconstitution.

General adverse events

The most common adverse reactions were liver test abnormalities, diarrhea, anemia, and hypokalemia.[Ref]

Cardiovascular

Gastrointestinal

Hematologic

Hepatic

Hypersensitivity

Metabolic

Renal

References

1. (2023) "Product Information. Xacduro (durlobactam-sulbactam)." La Jolla Pharmaceutical

Further information

Xacduro side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.