Skip to Content

Beta-lactamase inhibitors

What are Beta-lactamase inhibitors

Beta-lactamase inhibitors are a class of medicine that block the activity of beta-lactamase enzymes (also called beta-lactamases), preventing the degradation of beta-lactam antibiotics. They tend to have little antibiotic activity on their own.

Beta-lactamase enzymes are produced by certain strains of the following bacteria: Bacteroides species, Enterococcus species, Hemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae, and Staphylococcus species, either constitutively or on exposure to antimicrobials.

Beta-lactamases cleave the beta-lactam ring of susceptible penicillins and cephalosporins, inactivating the antibiotic. Some antimicrobials (eg, cefazolin and cloxacillin) are naturally resistant to certain beta-lactamases. The activity of the beta-lactams: amoxicillin, ampicillin, piperacillin, and ticarcillin, can be restored and widened by combining them with a beta-lactamase inhibitor.

Clavulanic acid, sulbactam, and tazobactam are all beta-lactamase inhibitors.

List of Beta-lactamase inhibitors:

Filter by:
Drug NameView by: Brand | Generic Reviews Avg. Ratings
Augmentin XR (Pro, More...)
generic name: amoxicillin/clavulanate
3 reviews
Unasyn (Pro, More...)
generic name: ampicillin/sulbactam
2 reviews
Zosyn (Pro, More...)
generic name: piperacillin/tazobactam
3 reviews
Amoclan (Pro, More...)
generic name: amoxicillin/clavulanate
0 reviews
Augmentin (Pro, More...)
generic name: amoxicillin/clavulanate
253 reviews
Augmentin ES-600 (Pro, More...)
generic name: amoxicillin/clavulanate
2 reviews
Timentin (Pro, More...)
generic name: clavulanate/ticarcillin
0 reviews