Voxzogo Side Effects

Generic name: vosoritide

Medically reviewed by Drugs.com. Last updated on Nov 15, 2024.

Note: This document provides detailed information about Voxzogo Side Effects associated with vosoritide. Some dosage forms listed on this page may not apply specifically to the brand name Voxzogo.

Applies to vosoritide: subcutaneous powder for solution.

Serious side effects of Voxzogo

Along with its needed effects, vosoritide (the active ingredient contained in Voxzogo) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking vosoritide:

More common side effects

• blurred vision
• chills
• confusion
• cough
• diarrhea
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fever
• general feeling of discomfort or illness
• headache
• joint pain
• loss of appetite
• muscle aches and pains
• nausea
• runny nose
• shivering
• sore throat
• sweating
• trouble sleeping
• unusual tiredness or weakness
• vomiting

Other side effects of Voxzogo

Some side effects of vosoritide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• difficulty in moving
• dry skin
• ear pain
• feeling of constant movement of self or surroundings
• hives, itching, rash, redness, swelling, or warmth at the injection site
• muscle pain or stiffness
• pain in the joints
• sensation of spinning
• stomach pain
• unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

For healthcare professionals

Applies to vosoritide: subcutaneous powder for injection.

General adverse events

The most common adverse effects were injection site reactions, vomiting, arthralgia, gastroenteritis and decreased blood pressure.^[Ref]

Cardiovascular

• Very common (10% or more): Decreased blood pressure (13%)^[Ref]

Dermatologic

• Common (1% to 10%): Dry skin^[Ref]

Gastrointestinal

• Very common (10% or more): Vomiting (27%), gastroenteritis (13%), diarrhea (10%)
• Common (1% to 10%): Nausea^[Ref]

Hypersensitivity

• Common (1% to 10%): Seasonal allergy^[Ref]

Immunologic

• Very common (10% or more): Anti-drug antibodies (35%)^[Ref]

Local

• Very common (10% or more): Injection site reactions (85%) including injection site erythema (75%), injection site swelling (62%), and injection site urticaria (25%)
• Frequency not reported: Injection site pain, injection site bruising, injection site pruritus, injection site hemorrhage, injection site discoloration, injection site induration^[Ref]

Metabolic

• Common (1% to 10%): Increased alkaline phosphatase^[Ref]

Musculoskeletal

• Very common (10% or more): Arthralgia (15%)^[Ref]

Nervous system

• Common (1% to 10%): Dizziness (included dizziness, syncope, presyncope, procedural dizziness, vertigo)^[Ref]

Other

• Common (1% to 10%): Ear pain, fatigue^[Ref]

Respiratory

• Very common (10% or more): Influenza (10%)^[Ref]

Further information

Voxzogo side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer