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Tretten Side Effects

Generic Name: factor XIII

Note: This page contains side effects data for the generic drug factor XIII. It is possible that some of the dosage forms included below may not apply to the brand name Tretten.

For the Consumer

Applies to factor XIII: intravenous powder for solution

As well as its needed effects, factor XIII (the active ingredient contained in Tretten) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking factor XIII, check with your doctor or nurse immediately:

More common:
  • Bloody nose
  • bruise
  • collection of blood under the skin
  • deep, dark purple bruise
  • fever
  • itching, pain, redness, or swelling
Incidence not known:
  • Chest pain
  • cough
  • dizziness or fainting
  • hives
  • pain in the chest, groin, or legs, especially the calves
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red, scaly, swollen, or peeling areas of the skin
  • severe, sudden headache
  • shortness of breath
  • tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
  • unusual tiredness or weakness

Minor Side Effects

Some factor XIII side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Difficulty with moving
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • muscle aches and pains

For Healthcare Professionals

Applies to factor XIII: intravenous powder for injection

Hypersensitivity

Hypersensitivity side effects have included allergy, rash, pruritus, and erythema, chills/rise in temperature, arthralgia, headache, elevated thrombin antithrombin levels, and an increase in hepatic enzymes.[Ref]

Hematologic

Hematologic side effects have included factor XIII (the active ingredient contained in Tretten) inhibitor formation.[Ref]

Cardiovascular

Cardiovascular side effects have included thrombosis and embolism.[Ref]

General

General side effects have included flu-like syndrome and pyrexia.[Ref]

Gastrointestinal

Gastrointestinal side effects have included abdominal pain, diarrhea and vomiting.[Ref]

Musculoskeletal

Musculoskeletal side effects have included contusion, joint injury, limb injury, road traffic accident, and arthralgia.[Ref]

Respiratory

Respiratory side effects have included upper respiratory tract infection and epistaxis.[Ref]

Nervous system

Nervous system side effects have included headache and head injury.[Ref]

Immunologic

Immunologic side effects have included allergic/anaphylactic reaction (including cutaneous reactions, alteration in blood pressure, nausea, dyspnea, fever, and chills).[Ref]

References

1. "Product Information. Corifact (factor XIII)." CSL Behring, King of Prussia, PA.

It is possible that some side effects of Tretten may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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