Skip to main content

Tetanus immune globulin Side Effects

Medically reviewed by Last updated on Aug 27, 2022.

For the Consumer

Applies to tetanus immune globulin: intramuscular solution

Side effects requiring immediate medical attention

Along with its needed effects, tetanus immune globulin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tetanus immune globulin:


  • Difficulty in breathing or swallowing
  • hives
  • itching, especially of soles or palms
  • reddening of skin, especially around ears
  • swelling of eyes, face, or inside of nose
  • unusual tiredness or weakness, sudden and severe

For Healthcare Professionals

Applies to tetanus immune globulin: intramuscular solution


Frequency not reported: Slight soreness at the injection site[Ref]


Frequency not reported: Nephrotic syndrome[Ref]


Very rare (less than 0.01%): Sensitization to repeated injections of human immunoglobulin

Frequency not reported: Anaphylactic shock[Ref]


Frequency not reported: Slight temperature elevations[Ref]


Frequency not reported: Angioneurotic edema[Ref]


1. "Product Information. Hypertet S/D (tetanus immune globulin)." Bayer Inc (2019):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.