Sars-cov-2 (covid-19) Mrna-lnp Vaccine (cvx 310) Side Effects
Applies to sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310): intramuscular suspension.
General adverse events
The most commonly reported side effects included injection site pain, fatigue, and headache.[Ref]
Cardiovascular
- Postmarketing reports: Myocarditis, pericarditis
Dermatologic
- Frequency not reported: Hyperhidrosis, night sweats
- Postmarketing reports: Pruritus, rash, urticaria
Gastrointestinal
- Very common (10% or more): Diarrhea (up to 11.1%)
- Common (1% to 10%): Vomiting
- Frequency not reported: Nausea
Hematologic
- Common (1% to 10%): Lymphadenopathy
Hypersensitivity
- Postmarketing reports: Anaphylaxis, angioedema, other hypersensitivity reactions (e.g., pruritus, rash, urticaria), severe allergic reactions
Local
- Very common (10% or more): Injection site pain (up to 90.5%), injection site swelling (up to 11.8%), injection site redness (up to 10.4%)
- Postmarketing reports: Extremity (arm) pain
Metabolic
- Frequency not reported: Decreased appetite
Musculoskeletal
- Very common (10% or more): Chills (up to 49.2%), muscle pain (up to 45.5%), new/worsened muscle pain (up to 39.3%), joint pain (up to 27.5%), new/worsened joint pain (up to 23.8%)
Nervous system
- Very common (10% or more): Headache (up to 75.5%)
- Frequency not reported: Bell's palsy/facial paralysis, lethargy
- Postmarketing reports: Dizziness, syncope
Other
- Very common (10% or more): Fatigue (up to 77.5%), use of antipyretic or pain medication (up to 50.8%), fever (up to 24.3%)
- Frequency not reported: Asthenia, malaise, febrile seizures
See also:
References
1. (2025) "Product Information. Comirnaty (2025-2026) PF (cvx 309) (SARS-CoV-2 (COVID-19) mRNA-LNP vaccine (cvx 309))." Pfizer Inc.
More about sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
Further information
Sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310) side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.