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Phenylephrine / Tropicamide Ophthalmic Side Effects

Medically reviewed by Drugs.com. Last updated on Jun 9, 2024.

Applies to phenylephrine / tropicamide ophthalmic: ophthalmic solution.

It is very important that your doctor check your or your child's progress closely while you are receiving this medicine. This is to make sure that the medicine is working properly and that the infection is cleared up completely. Blood tests may be needed to check for unwanted effects.

Check with your doctor right away if you have mood or mental changes or unusual behavior, including disorientation to time or place, failure to recognize people, hyperactivity, or restlessness.

Check with your doctor right away if you have blurred vision, change in vision, or loss of vision. These maybe symptoms of increased pressure in the eye.

This medicine may cause rebound miosis (narrowing of the pupils) a day after receiving this medicine. Talk to your doctor about this concern.

This medicine may cause blurred vision. Do not drive or do anything else that could be dangerous after receiving this medicine until you know how this medicine affects you.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects

Along with its needed effects, phenylephrine / tropicamide ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking phenylephrine / tropicamide ophthalmic:

Incidence not known

  • blurred vision
  • change in color vision
  • chest pain or discomfort
  • cold, clammy, pale skin
  • difficulty seeing at night
  • dizziness
  • eye discomfort
  • increased sensitivity of the eyes to sunlight
  • irregular heartbeat
  • loss of vision
  • mood or mental changes
  • muscle stiffness or tightness
  • painful irritation of the clear front part of the eye
  • slow heart rate
  • trouble breathing
  • unusual behavior, such as disorientation to time or place, failure to recognize people, hyperactivity, or restlessness
  • weakness

Other side effects

Some side effects of phenylephrine / tropicamide ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • dry mouth
  • headache
  • nausea

See also:

More about phenylephrine / tropicamide ophthalmic

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Further information

Phenylephrine/tropicamide ophthalmic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.