Odevixibat Side Effects
Medically reviewed by Drugs.com. Last updated on Dec 30, 2024.
Applies to odevixibat: oral capsule, oral pellet.
Precautions
It is very important that your doctor check your or your child's progress at regular visits to see if the medicine is working properly and to decide if you should continue to take it. Blood tests may be needed to check for any unwanted effects.
This medicine may cause diarrhea. If you have any questions or if diarrhea continues or gets worse, check with your doctor.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Serious side effects of odevixibat
Along with its needed effects, odevixibat may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking odevixibat:
More common side effects
- clay-colored stools
- confusion
- dark urine
- decreased urination
- diarrhea
- dizziness
- dry mouth
- fainting
- fever
- headache
- increased heart rate
- lightheadedness
- loss of appetite
- nausea
- rapid breathing
- skin rash
- stomach pain, fullness, or tenderness
- sunken eyes
- swelling of the feet or lower legs
- thirst
- unusual tiredness or weakness
- vomiting
- wrinkled skin
- yellow eyes or skin
Less common side effects
- fracture
For healthcare professionals
Applies to odevixibat: oral capsule, oral pellet.
General adverse events
The most commonly reported side effects included diarrhea, increased transaminases, vomiting, and abdominal pain.[Ref]
Gastrointestinal
- Very common (10% or more): Diarrhea (up to 39.1%), vomiting (up to 17.4%), abdominal pain (up to 15.8%)[Ref]
Hepatic
- Very common (10% or more): Increased transaminases (ALT, AST) (up to 21.1%), increased blood bilirubin (up to 13%)
- Common (1% to 10%): Cholelithiasis[Ref]
Metabolic
- Very common (10% or more): Fat-soluble vitamin deficiency (vitamin A, D, E) (up to 15.8%)
- Common (1% to 10%): Dehydration[Ref]
Hematologic
- Very common (10% or more): Splenomegaly (up to 10.5%)[Ref]
Musculoskeletal
- Common (1% to 10%): Fracture[Ref]
See also:
Livmarli
Livmarli is used to treat Alagille syndrome (ALGS) in people 3 months and older and progressive ...
Bylvay
Bylvay (odevixibat) is an oral capsule that may be used to treat itching (pruritus) caused by ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Maralixibat
Maralixibat systemic is used for cholestatic pruritus in alagille syndrome, cholestatic pruritus in ...
References
1. (2021) "Product Information. Bylvay (odevixibat)." Albireo Pharma, Inc.
More about odevixibat
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- Drug class: miscellaneous GI agents
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Further information
Odevixibat side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.