Odevixibat Side Effects
Medically reviewed by Drugs.com. Last updated on Dec 19, 2024.
Applies to odevixibat: oral capsule, oral pellet.
Serious side effects of odevixibat
Along with its needed effects, odevixibat may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking odevixibat:
More common side effects
- clay-colored stools
- confusion
- dark urine
- decreased urination
- diarrhea
- dizziness
- dry mouth
- fainting
- fever
- headache
- increased heart rate
- lightheadedness
- loss of appetite
- nausea
- rapid breathing
- skin rash
- stomach pain, fullness, or tenderness
- sunken eyes
- swelling of the feet or lower legs
- thirst
- unusual tiredness or weakness
- vomiting
- wrinkled skin
- yellow eyes or skin
Less common side effects
- fracture
For healthcare professionals
Applies to odevixibat: oral capsule, oral pellet.
General adverse events
The most commonly reported side effects included diarrhea, increased transaminases, vomiting, and abdominal pain.[Ref]
Gastrointestinal
- Very common (10% or more): Diarrhea (up to 39.1%), vomiting (up to 17.4%), abdominal pain (up to 15.8%)[Ref]
Hepatic
- Very common (10% or more): Increased transaminases (ALT, AST) (up to 21.1%), increased blood bilirubin (up to 13%)
- Common (1% to 10%): Cholelithiasis[Ref]
Metabolic
- Very common (10% or more): Fat-soluble vitamin deficiency (vitamin A, D, E) (up to 15.8%)
- Common (1% to 10%): Dehydration[Ref]
Hematologic
- Very common (10% or more): Splenomegaly (up to 10.5%)[Ref]
Musculoskeletal
- Common (1% to 10%): Fracture[Ref]
References
1. (2021) "Product Information. Bylvay (odevixibat)." Albireo Pharma, Inc.
More about odevixibat
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- Drug class: miscellaneous GI agents
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Further information
Odevixibat side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
