Skip to main content

Luveris Side Effects

Generic name: lutropin alfa

Medically reviewed by Last updated on Aug 22, 2022.

Note: This document contains side effect information about lutropin alfa. Some dosage forms listed on this page may not apply to the brand name Luveris.

Applies to lutropin alfa: parenteral injection.

Side effects include:

Headache, nausea, ovarian hyperstimulation, breast pain, abdominal pain, ovarian cyst.

For Healthcare Professionals

Applies to lutropin alfa: subcutaneous powder for injection.


The most commonly reported adverse events reported have included headache, pelvic and abdominal pain, nausea, injection site reactions, and mild or moderate ovarian hyperstimulation syndrome (OHSS).[Ref]


Common (1% to 10%): Ovarian hyper-stimulation syndrome (OHSS), ovarian cyst, breast pain, pelvic pain

Frequency not reported: Abortion, breast enlargement, endometrial disorder, genital edema, hemorrhage in pregnancy, leucorrhoea, pelvic pain, pelvic congestion, ectopic pregnancy, premenstrual tension, uterine disorder not otherwise specified, uterine spasm, vaginal candidiasis, vaginal hemorrhage, vaginitis


Common (1% to 10%): Injection site reactions[Ref]

During clinical trials, 7.4% of patients reported mild and moderate injection site reactions consisting of bruising, pain, redness, itching, or swelling; there were no reports of severe injection site reactions[Ref]


Common (1% to 10%): Dysmenorrhea

Frequency not reported: Dysuria, micturition frequency change[Ref]


Common (1% to 10%): Abdominal pain, abdominal discomfort, nausea, vomiting, diarrhea, flatulence, constipation,

Frequency not reported: Tooth caries[Ref]


Very rare (less than 0.01%): Thromboembolism

Frequency not reported: Vasodilation[Ref]


Frequency not reported: Asthenia, back pain, leg cramps, leg pain, skeletal pain[Ref]

Nervous system

Common (1% to 10%): Headache

Frequency not reported: Hyperkinesia, dizziness[Ref]


Frequency not reported: Cough, dyspnea, pharyngitis, rhinitis[Ref]


Mild to severe hypersensitivity reactions including anaphylactic reactions and shock have been reported.

Very rare (less than 0.01%): Hypersensitivity reactions


Frequency not reported: Herpes simplex, infection, influenza-like symptoms, Klebsiella


Frequency not reported: Conjunctivitis


Frequency not reported: Anxiety, depression, insomnia, nervousness, somnolence


There have been reports of ovarian and other reproductive system neoplasms, both benign and malignant, in women who have undergone multiple treatment regimens for infertility. It has not been established whether or not treatment with gonadotropins increases the risk of these tumors in infertile women.

Frequency not reported: Neoplasms


Frequency not reported: Fever, not otherwise specified; fever


Frequency not reported: Acne, nail disorder, rash dry skin

More about Luveris (lutropin alfa)

Patient resources

Professional resources

Related treatment guides


1. "Product Information. Luveris (lutropin alfa)." Serono Laboratories Inc (2004):

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "Canadian Product Information." O 0 (2015):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.