Leniolisib Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 10, 2024.

Applies to leniolisib: oral tablets.

Side effects include:

Most common adverse reactions (incidence >10%) reported with leniolisib include headache, sinusitis, atopic dermatitis.

For healthcare professionals

Applies to leniolisib: oral tablet.

General adverse events

The most common adverse reactions included headache, sinusitis, and atopic dermatitis.^[Ref]

Cardiovascular

• Very common (10% or more): Tachycardia/sinus tachycardia (10%)

Dermatologic

• Very common (10% or more): Atopic dermatitis/eczema (14%), alopecia (10%)

Gastrointestinal

• Very common (10% or more): Vomiting (14%), diarrhea (10%)

Hematologic

Decreased neutrophil count (33%)

An absolute neutrophil count (ANC) between 500 and 1500 cells/mcL developed in 33% of patients during clinical studies. No patients developed an ANC less than 500 cells/mcL and there were no reports of infection associated with neutropenia.

Hypersensitivity

• Postmarketing reports: Hypersensitivity/anaphylaxis

Musculoskeletal

• Very common (10% or more): Back pain (10%), neck pain (10%)

Nervous system

• Very common (10% or more): Headache (up to 24%)

Other

• Very common (10% or more): Pyrexia (up to 19%), weight gain/increased (14%), otitis externa (14%), fatigue (10%)

Respiratory

• Very common (10% or more): COVID-19 (30%), upper respiratory tract infections (27%), sinusitis (up to 19%), respiratory tract infection (14%)

See also:

Further information

Leniolisib side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer