Korsuva Side Effects

Generic name: difelikefalin

Medically reviewed by Drugs.com. Last updated on Jul 20, 2024.

Note: This document provides detailed information about Korsuva Side Effects associated with difelikefalin. Some dosage forms listed on this page may not apply specifically to the brand name Korsuva.

Applies to difelikefalin: intravenous solution.

Serious side effects of Korsuva

Along with its needed effects, difelikefalin (the active ingredient contained in Korsuva) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking difelikefalin:

More common

• dizziness
• falls
• trouble in walking

Less common

• confusion
• irregular heartbeat
• mental depression or anxiety
• nausea or vomiting
• nervousness
• nightmares or unusually vivid dreams
• numbness or tingling in the hands, feet, or lips
• sleepiness or unusual drowsiness
• stomach pain
• trouble breathing
• weakness or heaviness of the legs

Other side effects of Korsuva

Some side effects of difelikefalin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• diarrhea

Less common

• headache

For Healthcare Professionals

Applies to difelikefalin: intravenous solution.

General

The most commonly reported adverse effects have included diarrhea, dizziness, nausea, back pain, gait disturbances, paresthesia, hyperkalemia, headache, vomiting, somnolence, and mental status change.^[Ref]

Dermatologic

• Postmarketing reports: Drug reaction with eosinophilia and systemic symptoms (DRESS)^[Ref]

DRESS has been reported in only one individual case report, and its causal relationship is yet to be established.^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea, diarrhea
• Uncommon (0.1% to 1%): Vomiting^[Ref]

Metabolic

• Common (1% to 10%): Hyperkalemia^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, headache, somnolence, gait disturbances, paresthesia^[Ref]

Gait disturbances includes preferred terms of falls and gait disturbances.

Paresthesia includes hypoesthesia, paresthesia oral and hypoesthesia oral.^[Ref]

Psychiatric

• Common (1% to 10%): Mental status change^[Ref]

Mental status change includes preferred terms of confusional state and mental status change.^[Ref]

Musculoskeletal

• Common (1% to 10%): Muscle pain, back pain^[Ref]

Other

• Frequency not reported: Fatigue^[Ref]

Frequently asked questions

• How does Korsuva work?

Further information

Korsuva side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer