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Ipol Side Effects

Generic Name: poliovirus vaccine, inactivated

Note: This page contains information about the side effects of poliovirus vaccine, inactivated. Some of the dosage forms included on this document may not apply to the brand name Ipol.

For the Consumer

Applies to poliovirus vaccine, inactivated: injection injectable, injection suspension

In addition to its needed effects, some unwanted effects may be caused by poliovirus vaccine, inactivated (the active ingredient contained in Ipol). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking poliovirus vaccine, inactivated, check with your doctor or nurse immediately:

Symptoms of allergic reaction
  • Difficulty with breathing or swallowing
  • hives
  • itching, especially of the feet or hands
  • reddening of the skin, especially around ears
  • swelling of the eyes, face, or inside of the nose
  • unusual tiredness or weakness (sudden and severe)
More common:
  • Fever over 102° F (39° C)

Minor Side Effects

Some of the side effects that can occur with poliovirus vaccine, inactivated may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Irritability
  • loss of appetite
  • tiredness
Less common:
  • Itching or skin rash
  • redness, soreness, hard lump, tenderness, or pain at the place of injection

For Healthcare Professionals

Applies to poliovirus vaccine, inactivated: injectable suspension


Very common (10% or more): Injection site pain (34%), local tenderness (29.4%), local swelling (11.4%)
Common (1% to 10%): Local erythema
Uncommon (0.1% to 1%): Injection site mass
Postmarketing reports: Injection site reaction (including injection site rash)[Ref]


Very common (10% or more): Temperature over 102F (38%)
Common (1% to 10%): Persistent crying
Frequency not reported: Death
Postmarketing reports: Pyrexia[Ref]


Very common (10% or more): Irritability (64.5%), tiredness (60.7%) fussiness, sleepiness
Postmarketing reports: Agitation[Ref]


Very common (10% or more): Anorexia (16.6%)[Ref]


Common (1% to 10%): Vomiting, diarrhea[Ref]

Nervous system

Frequency not reported: Guillain-Barre syndrome
Postmarketing reports: Convulsion, febrile convulsion, headache, paresthesia[Ref]


Postmarketing reports: Type I hypersensitivity reaction (including allergic reaction, anaphylactic reaction, and anaphylactic shock)[Ref]


Postmarketing reports: Arthralgia, myalgia[Ref]


Postmarketing reports: Lymphadenopathy[Ref]


Postmarketing reports: Rash, urticaria[Ref]


1. "Product Information. Ipol (poliovirus vaccine, inactivated)." Aventis Pharmaceuticals, Swiftwater, PA.

2. Cerner Multum, Inc. "Australian Product Information." O 0

Not all side effects for Ipol may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.