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Ipol Side Effects

Generic Name: poliovirus vaccine, inactivated

Note: This page contains information about the side effects of poliovirus vaccine, inactivated. Some of the dosage forms included on this document may not apply to the brand name Ipol.

For the Consumer

Applies to poliovirus vaccine, inactivated: injection injectable, injection suspension

In addition to its needed effects, some unwanted effects may be caused by poliovirus vaccine, inactivated (the active ingredient contained in Ipol). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking poliovirus vaccine, inactivated, check with your doctor or nurse immediately:

Symptoms of allergic reaction
  • Difficulty with breathing or swallowing
  • hives
  • itching, especially of the feet or hands
  • reddening of the skin, especially around ears
  • swelling of the eyes, face, or inside of the nose
  • unusual tiredness or weakness (sudden and severe)
More common:
  • Fever over 102° F (39° C)

Minor Side Effects

Some of the side effects that can occur with poliovirus vaccine, inactivated may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Irritability
  • loss of appetite
  • tiredness
Less common:
  • Itching or skin rash
  • redness, soreness, hard lump, tenderness, or pain at the place of injection

For Healthcare Professionals

Applies to poliovirus vaccine, inactivated: injectable suspension


Local side effects associated with intramuscular administration have included erythema, swelling, and tenderness at the injection site.[Ref]


Other side effects have included fever >102.2 degrees F, irritability, tiredness, and persistent crying in infants following concomitant vaccination with poliovirus and DTP vaccine. The frequency and severity were similar to adverse effects for DTP vaccine alone.[Ref]


Gastrointestinal side effects have included anorexia and vomiting in infants, following concomitant vaccination with poliovirus and DTP vaccine. The frequency and severity were similar to adverse effects for DTP vaccine alone.[Ref]

Nervous system

Nervous system side effects temporally associated with a different inactivated poliovirus vaccine have included Guillain-Barre Barre syndrome.[Ref]


1. "Product Information. Ipol (poliovirus vaccine, inactivated)." Aventis Pharmaceuticals, Swiftwater, PA.

Not all side effects for Ipol may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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