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Dasiglucagon Side Effects

Medically reviewed by Drugs.com. Last updated on Dec 2, 2024.

Applies to dasiglucagon: subcutaneous solution.

Precautions

Patients with diabetes should be aware of the symptoms of hypoglycemia (low blood sugar). These symptoms may develop in a very short time and may result from:

Unless corrected, hypoglycemia will lead to unconsciousness, seizures, and possibly death. Early symptoms of hypoglycemia include: anxious feeling, behavior change similar to being drunk, blurred vision, cold sweats, confusion, cool pale skin, difficulty in concentrating, drowsiness, excessive hunger, fast heartbeat, headache, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, and unusual tiredness or weakness.

Symptoms of hypoglycemia can differ from person to person. It is important that you learn your own signs of low blood sugar so that you can treat it quickly. It is a good idea also to check your blood sugar to confirm that it is low.

You should know what to do if symptoms of low blood sugar occur. Eating or drinking something containing sugar when symptoms of low blood sugar first appear will usually prevent them from getting worse, and will probably make the use of dasiglucagon unnecessary. Good sources of sugar include glucose tablets or gel, corn syrup, honey, sugar cubes or table sugar (dissolved in water), fruit juice, or non-diet soft drinks. If a meal is not scheduled soon (1 hour or less), you should also eat a light snack, such as crackers and cheese or half a sandwich or drink a glass of milk to keep your blood sugar from going down again. You should not eat hard candy or mints because the sugar will not get into your blood stream quickly enough. You also should not eat foods high in fat such as chocolate because the fat slows down the sugar entering the blood stream. After 10 to 20 minutes, check your blood sugar again to make sure it is not still too low.

Tell someone to take you to your doctor or to a hospital right away if the symptoms do not improve after eating or drinking a sweet food. Do not try to drive, use machines, or do anything dangerous until you have eaten a sweet food.

Tell your doctor right away if you have blurred vision, dizziness, nervousness, headache, pounding in the ears, or slow or fast heartbeat. These may be symptoms of high blood pressure.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, any swelling of your hands, face, or mouth, or lightheadedness, dizziness, or fainting while you are receiving this medicine.

If it becomes necessary to inject dasiglucagon, a family member or friend should know the following:

Keep your doctor informed of any hypoglycemic episodes or use of dasiglucagon even if the symptoms are successfully controlled and there seem to be no continuing problems. Complete information is necessary for the doctor to provide the best possible treatment of any condition.

Replace your supply of dasiglucagon as soon as possible, in case another hypoglycemic episode occurs.

Common side effects of dasiglucagon

Some side effects of dasiglucagon may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • diarrhea
  • nausea
  • vomiting

Serious side effects of dasiglucagon

Along with its needed effects, dasiglucagon may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dasiglucagon:

Incidence not known

  • blurred vision
  • chest pain, discomfort, or tightness
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, irregular, pounding, or racing heartbeat or pulse
  • headache
  • itching, skin rash
  • lightheadedness, dizziness, or fainting
  • loss of consciousness
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
  • swelling of the eyes or eyelids
  • sweating
  • trouble breathing
  • unusual tiredness or weakness

For healthcare professionals

Applies to dasiglucagon: subcutaneous solution.

General adverse events

The most commonly reported adverse reactions have included nausea, vomiting, headache, and injection site pain.[Ref]

Gastrointestinal

Local

Cardiovascular

Nervous system

See also:

References

1. (2021) "Product Information. Zegalogue Prefilled Syringe (dasiglucagon)." Zealand Pharma A/S

Further information

Dasiglucagon side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.