Apadamtase Alfa, Recombinant Side Effects
Medically reviewed by Drugs.com. Last updated on Jul 18, 2024.
Applies to apadamtase alfa, recombinant: intravenous powder for solution.
Serious side effects
Along with its needed effects, apadamtase alfa, recombinant may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking apadamtase alfa, recombinant:
More common side effects
Incidence not known
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- chest tightness
- confusion
- difficulty swallowing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast, pounding, or irregular heartbeat or pulse
- hives, itching, skin rash
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- nausea
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- restlessness
- unusual drowsiness, dullness, or feeling of sluggishness
- vomiting
Other side effects
Some side effects of apadamtase alfa, recombinant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
- diarrhea
- stomach pain
For healthcare professionals
Applies to apadamtase alfa, recombinant: intravenous kit.
General adverse events
The most common adverse reactions reported in 5% or more patients were headache, diarrhea, migraine, abdominal pain, nausea, upper respiratory tract infection, dizziness, and vomiting.[Ref]
Gastrointestinal
- Very common (10% or more): Diarrhea (16.7%), abdominal pain (12.5%), nausea (12.5%), vomiting (10.4%)[Ref]
Respiratory
- Very common (10% or more): Upper respiratory tract infection (12.5%)[Ref]
Nervous system
- Very common (10% or more): Headache (31.3%), migraine (14.6%), dizziness (10.4%)[Ref]
References
1. (2023) "Product Information. Adzynma (apadamtase alfa, recombinant)." Takeda Pharmaceuticals America
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Further information
Apadamtase alfa, recombinant side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.