Alglucerase Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 29, 2024.

Applies to alglucerase: injectable solution, intravenous solution.

Important warnings This medicine can cause some serious health issues

Alglucerase may improve the condition of the liver, spleen, bones, and blood cells in people with Type I Gaucher disease. However, alglucerase is not a cure for this condition.

Some people receiving an alglucerase injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel itchy, dizzy, light-headed, or have hives, stomach cramps, pain or tightness in your chest, trouble breathing, or swelling of your face, lips, tongue, or throat.

It may still be possible for you to receive alglucerase even after you have had a reaction to it.

There are other medications that can be given to you before your alglucerase infusion to help prevent any reaction symptoms.

Some people receiving an alglucerase injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel itchy, dizzy, light-headed, or have hives, stomach cramps, pain or tightness in your chest, trouble breathing, or swelling of your face, lips, tongue, or throat.

It may still be possible for you to receive alglucerase after you have had a reaction to it. There are other medications that can be given to you before your alglucerase infusion to help prevent any reaction symptoms.

Call your doctor at once if you have any of these serious side effects:

• mouth sores;

• warmth, redness, or tingly feeling under your skin;

• easy bruising or bleeding;

• extreme weakness or tired feeling;

• swollen belly, stomach discomfort; or

• pale skin.

Some of these may be symptoms of your condition and not actual side effects of alglucerase.

Less serious side effects of alglucerase may include:

• hot flashes;

• changes in your menstrual periods;

• headache;

• back pain;

• swelling in your hands or feet;

• changes in your sense of smell;

• nausea, diarrhea, upset stomach;

• fever or chills; or

• any burning, itching, or swelling around the IV needle when the medicine is injected.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Further information

Alglucerase side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer