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Alglucerase (Intravenous)

Generic name: alglucerase [ al-GLOO-ser-ase ]
Brand name: Ceredase
Drug class: Lysosomal enzymes

Medically reviewed by Drugs.com. Last updated on Jan 22, 2024.

Uses for alglucerase

Alglucerase is used to treat Gaucher's disease caused by the lack of a certain enzyme, glucocerebrosidase, in the body. This enzyme is necessary for your body to use fats.

Alglucerase is made from human placenta tissue that is collected after a baby is born. Before it is used, the tissue is tested for hepatitis and human immunodeficiency virus (HIV). This is similar to the testing that a blood bank does on donated blood before it is given to anyone else.

Alglucerase is available with your doctor's prescription.

Before using alglucerase

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in a limited number of children. In effective doses, the medicine has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of alglucerase in the elderly with use in other age groups.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper use of alglucerase

This medicine will not cure Gaucher's disease but it does help control it. Therefore, you must continue to receive it if you expect to keep your condition under control. You may have to receive alglucerase for the rest of your life. If Gaucher's disease is not treated, it can cause serious blood, liver, skeletal, or spleen problems.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Precautions while using alglucerase

It is important that your doctor check your progress while you are receiving alglucerase to make sure that the dosage is correct for you.

Side Effects of alglucerase

Since alglucerase is made from human tissue, it is possible that diseases caused by viruses could be passed on. Examples of such diseases are hepatitis and HIV infection. These problems have not been reported to date, however, and are unlikely since the tissue is tested before being used. If you have questions or concerns about this, check with your doctor.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Commonly used brand name(s)

In the U.S.

Pharmacologic Class: Enzyme

More about alglucerase

Patient resources

Other brands

Ceredase

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.