Standardization Needed for Dialysis Initiation in Pregnancy
By Elana Gotkine HealthDay Reporter
WEDNESDAY, July 23, 2025 -- The initiation of dialysis in women with chronic kidney disease during pregnancy varies by clinical practice, signaling a need for standardized care in this population, according to a study published in the July issue of Kidney International Reports.
Jennifer H. Yo, M.B.B.S., M.P.H., from Monash Health in Melbourne, Australia, and colleagues examined dialysis initiation patterns in pregnancy in a multinational retrospective cohort study of women who delivered between Jan. 1, 2000, and Oct. 31, 2022. A total of 169 pregnancies in 149 women were included; eligible women had a prepregnancy estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m2 within 12 months of conception or a serum creatinine ≥150 μmol/L when first measured during pregnancy.
Overall, 46.7 percent of the women initiated dialysis during pregnancy at a median of 21.4 weeks of gestation. Regional differences were seen in initiation and dose (hours per week) of dialysis. The researchers found that women who started dialysis during pregnancy more often had adverse maternal and fetal outcomes than women who did not start dialysis during pregnancy. There were no significant associations seen between dialysis hours per week and adverse maternal and fetal outcomes. The mean change in eGFR at one year postpartum versus prepregnancy values was −8.4 mL/min/1.73 m2 in women not on dialysis.
"Our study findings provide much needed contemporary data on dialysis initiation during pregnancy and the maternal and fetal outcomes within a cohort of women with advanced CKD," the authors write. "The interclinician and regional differences in practice highlight the need for standardized care to optimize outcomes. Enhancing clinician education on prepregnancy counseling is essential, particularly in fostering proactive discussions about reproductive intentions and contraceptive needs."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted July 2025
Read this next
High Metabolic Syndrome Severity Linked to Development of CKD
FRIDAY, Aug. 15, 2025 -- High metabolic syndrome (MetS) severity, expressed by the continuous metabolic syndrome severity score (cMetS-S), is associated with development of...
Lupus Low Disease Activity State Attainable in Lupus Nephritis
THURSDAY, Aug. 14, 2025 -- In lupus nephritis, attainment of complete renal response (CRR)/partial renal response (PRR) and lupus low disease activity state (LLDAS) is associated...
Dietary Patterns Linked to Chronic Kidney Disease Risk
THURSDAY, Aug. 14, 2025 -- Compared with other dietary indices, Dietary Approaches to Stop Hypertension (DASH) and the Dietary Inflammatory Index (DII) provide chronic kidney...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.