Life's Crucial 9 Negatively Linked to Overactive Bladder
By Elana Gotkine HealthDay Reporter
WEDNESDAY, Feb. 5, 2025 -- Life's Crucial 9 (LC9), a recently proposed method for assessing cardiovascular health, has a strong negative correlation with overactive bladder (OAB), which is partially mediated by the weight-adjusted waist index (WWI), according to a study published online Jan. 5 in Frontiers in Nutrition.
Hongyang Gong, from the Fuzhou Hospital of Traditional Chinese Medicine Affiliated to Fujian University of Traditional Chinese Medicine in China, and colleagues examined the relationship between LC9 and OAB using data from the National Health and Nutrition Examination Survey and then examined whether WWI moderates the association.
The study included 25,319 participants, 5,038 of whom reported incidents of OAB. The researchers found that after multivariable adjustment, a 10-unit increase in LC9 was associated with a significant reduction in OAB (odds ratio, 0.72), while an increase of 1 unit in WWI was associated with a significantly increased risk for OAB (odds ratio, 1.40). When LC9 and WWI were categorized into quartiles, consistent results were seen. A linear negative correlation between the incidence of OAB and LC9 was indicated in a restricted cubic splines analysis. WWI mediated 13.89 percent of the relationship between LC9 and OAB.
"Our study provides new insights into the prevention and management of OAB, emphasizing that a comprehensive approach to improving cardiovascular health and addressing obesity may help reduce the prevalence of OAB," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted February 2025
Read this next
Health Care Expenditure Expected to Top GDP Growth 2024 to 2033
THURSDAY, July 3, 2025 -- The annual growth in national health spending is expected to be faster than average gross domestic product (GDP) growth during 2024 to 2033, according to...
Considerable Variation Seen in Commercial Pricing for Surgery Services
THURSDAY, July 3, 2025 -- Commercial pricing varies considerably for general surgery services, with facility prices exhibiting greater variability, according to a research letter...
Urinary Metal Levels Tied to Increased Risk for Later Heart Failure
THURSDAY, July 3, 2025 -- There are consistent associations between elevated urinary metal levels and increased heart failure risk over time across geographically diverse cohorts...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.