Skip to main content

Pod-Style E-Cigarettes May Have Higher Abuse Liability Than Nicotine Gum

By Lori Solomon HealthDay Reporter

Medically reviewed by Carmen Pope, BPharm. Last updated on May 29, 2025.

via HealthDay

THURSDAY, May 29, 2025 -- Modern pod-style electronic cigarette (ECIG) devices may have a higher abuse liability than nicotine gum in individuals with no history of cigarette smoking, according to a study published online May 20 in Nicotine & Tobacco Research.

Andrea R. Milstred, from West Virginia University in Morgantown, and colleagues compared the subjective and behavioral effects of pod-style ECIGs to nicotine gum. The analysis included 16 young adult users of pod-style ECIGs with no history of cigarette smoking.

The researchers found significant decreases in intention to vape from before to after use of ECIGs but not after 4-mg nicotine gum or placebo gum. Ratings of relief and satisfaction similarly were significantly higher for ECIGs than for either gum dose at both bouts. Although not significant, the crossover point was higher for ECIGs than for gum.

"People with ECIG experience, but who have never regularly smoked cigarettes, represent a growing population of nicotine users. Results demonstrate that modern ECIG devices are more reinforcing than nicotine gum and therefore have a higher abuse liability for this vulnerable population," the authors write. "There is a clear need to continue monitoring the use and effects of modern devices, especially given the rapid evolution of ECIG products to date."

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Read this next

Cannabis Use Disorder Linked to Increased Risk for Oral Cancer

FRIDAY, Aug. 1, 2025 -- Cannabis use disorder (CUD) is associated with an increased risk for oral cancer, according to a study published in the September issue of Preventive...

Stigma of Substance Use Disorder Varies by Condition, Provider

WEDNESDAY, July 30, 2025 -- Health care provider stigma toward substance use disorder (SUD) varies by condition and provider, according to a study published online July 23 in...

Potentially Dangerous Modifications to E-Cigarettes Common

TUESDAY, July 29, 2025 -- More than eight in 10 electronic cigarette users modify their device, often in potentially dangerous ways, according to a study published online July 9...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.