Lung Cancer Screening Adherence Rates Decline Annually After Baseline Screening
By Elana Gotkine HealthDay Reporter
THURSDAY, March 20, 2025 -- Screening adherence is associated with increased overall and early-stage lung cancer detection rates among individuals undergoing lung cancer screening (LCS); however, adherence rates appear to decrease following baseline screening, according to a study published online March 18 in JAMA Network Open.
Roger Y. Kim, M.D., from the University of Pennsylvania in Philadelphia, and colleagues conducted a retrospective cohort study involving adults aged 55 to 75 years who formerly or currently smoked and underwent baseline LCS (T0) between Jan. 1, 2015, and Dec. 31, 2018, to examine annual LCS adherence rates across two subsequent LCS rounds (T1 and T2).
Overall, 10,170 individuals received baseline LCS. The researchers found that during rounds T1 and T2, 61.2 and 50.5 percent of eligible patients were adherent, respectively. There was a significant association for T1 adherence with T2 adherence. A total of 2.7 percent of participants were diagnosed with lung cancer across 36 months of follow-up. During rounds T0, T1, and T2, incident lung cancer diagnosis rates were 1.3, 0.7, and 0.8 percent, respectively. Higher lung cancer diagnosis rates were seen among those who were LCS-adherent during both rounds T1 (1.0 versus 0.2 percent) and T2 (1.3 versus 0.2 percent). The proportion of early-stage lung cancers was higher among individuals adherent to screening at T2 versus those not adherent (73.0 versus 25.0 percent).
"The finding that annual LCS adherence rates decreased across subsequent rounds of screening supports the use of annual adherence as a quality metric for LCS programs seeking to maximize the benefits of LCS for early lung cancer detection and, ultimately, reduced lung cancer-related deaths," the authors write.
Several authors disclosed ties to the biopharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted March 2025
Read this next
Female PCPs Have Equal/Better Quality Outcomes Than Male PCPs
TUESDAY, May 20, 2025 -- Female primary care physicians (PCPs) in value-based payment models have equal or better quality outcomes and higher earning than their male counterparts...
Accurate Risk Prediction Model Developed for Pediatric Pneumonia
TUESDAY, May 20, 2025 -- An accurate risk prediction model has been developed for children younger than 14 years with community-acquired pneumonia (CAP), according to a study...
AAP Updates Guidelines for Pediatric Atopic Dermatitis Management
MONDAY, May 19, 2025 -- In a clinical report published online May 19 in Pediatrics, the American Academy of Pediatrics presents updated guidance for the treatment of children...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.