Longer In-Bed Time Linked to Small Vessel Disease Burden in TIA/Mild Stroke
By Elana Gotkine HealthDay Reporter
FRIDAY, May 30, 2025 -- For adult patients with transient ischemic attack (TIA)/mild stroke, disturbed sleep is associated with greater cerebral small vessel disease (SVD) burden and worse cognitive outcomes, according to a study published online May 28 in Neurology.
Dillys Xiaodi Liu, Ph.D., of the University of Hong Kong, and colleagues examined the associations of self-reported sleep metrics with neuroimaging markers of SVD and cognitive performance in 211 adult patients with TIA/mild stroke recruited from the Mild Stroke Study 3 and 211 adult patients with TIA/mild stroke recruited from the University of Hong Kong stroke cohort during 2018 to 2022.
The researchers found that longer in-bed time was independently associated with greater global SVD (odds ratio, 1.27 per one standard deviation [SD] increase) and Fazekas periventricular white matter hyperintensity burden (odds ratio, 1.53 per one SD increase). There was an independent association seen for longer sleep duration with presence of cerebral microbleeds (odds ratio, 1.42 per one SD increase). After covariate adjustment, longer in-bed time was associated with lower total Montreal Cognitive Assessment score (standardized β = −0.58).
"More research is needed to confirm these findings and also to look at whether prolonged sleep has negative effects on people who have never had a stroke or TIA," coauthor Joanna M. Wardlaw, M.D., from the University of Edinburgh in the United Kingdom, said in a statement. "Of course, research is also needed on whether improving people's sleep patterns after stroke could ward off some of these possible detrimental effects."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted May 2025
Read this next
Consistent Physical Activity Linked to Reduced All-Cause, CVD Mortality
FRIDAY, July 11, 2025 -- Consistently and increasingly accumulated physical activity (PA) is associated with a reduced risk for all-cause and cardiovascular disease (CVD)...
Increased Liver Enzyme Levels Seen With Use of Cannabidiol in Adults
THURSDAY, July 10, 2025 -- Use of cannabidiol (CBD) within the range consumers are taking with unregulated CBD products is associated with increased liver enzyme levels, according...
Majority of Patients With Lyme Disease Do Not Follow Up With Clinician
THURSDAY, July 10, 2025 -- Only 34 percent of patients with erythema migrans >5 cm are positive for Lyme disease by a standard two-tier testing (STTT) algorithm, and of...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.