Hormone Therapy Tied to Worse Bladder Health in Postmenopausal Women
By Lori Solomon HealthDay Reporter
TUESDAY, May 6, 2025 -- Hormone therapy use is linked to worse bladder health in postmenopausal women, according to a study published online April 29 in Menopause.
Camille P. Vaughan, M.D., from the Atlanta VA Geriatric Research Education and Clinical Center at Emory University, and colleagues evaluated associations between menopause status and hormone use with bladder health and lower urinary tract symptoms (LUTS). The analysis included 3,126 community-dwelling adult women.
The researchers found that across multiple bladder health scales and bladder function indices, perimenopause and postmenopause status were associated with worse scores versus premenopause status. Perimenopausal women were more likely to report urgency urinary incontinence (odds ratio, 2.27) and other LUTS versus premenopausal women. In postmenopausal women, hormone use was associated with worse bladder health.
"While it is not possible to determine the directionality of the association between hormone use and bladder health and LUTS, these results do not support routine recommendations for hormone use in the perimenopausal and postmenopausal periods," the authors write. "Future research should continue to investigate the nuances of this relationship, enabling more effective prevention and management strategies for women with and without LUTS before and during menopause."
Two authors disclosed ties to the medical technology industry.
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted May 2025
Read this next
ASCO: Elinzanetant Cuts Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy
TUESDAY, June 3, 2025 -- For women with moderate-to-severe vasomotor symptoms associated with endocrine therapy for hormone receptor (HR)-positive breast cancer, elinzanetant, a...
Earlier Natural Menopause Risk Increased for Women in Socially Vulnerable Neighborhoods
THURSDAY, May 29, 2025 -- Women residing in U.S. neighborhoods with high social vulnerability have a higher risk for earlier natural menopause, according to a study published...
High Midlife Cortisol Tied to Later Risk for Alzheimer Disease in Postmenopausal Women
THURSDAY, May 29, 2025 -- Postmenopausal women with high midlife cortisol have an increased risk for Alzheimer disease (AD), according to a study published online April 24...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.