Geriatric Nutritional Risk Index Predictive for Overactive Bladder
By Elana Gotkine HealthDay Reporter
MONDAY, April 7, 2025 -- The Geriatric Nutritional Risk Index (GNRI) is a reliable predictive marker for overactive bladder (OAB) in the elderly, according to a study published online Feb. 10 in Frontiers in Nutrition.
Wei Zheng, from Hangzhou Medical College in China, and colleagues examined the association between GNRI and the prevalence of OAB in a study involving 17,161 elderly individuals from the National Health and Nutrition Examination Survey between 2005 and 2018. Subgroup analyses were used to assess influencing factors, and the predictive utility of GNRI was examined. A mediation analysis was conducted to assess the influence of inflammatory response and cognitive function on the interaction between GNRI and OAB.
The researchers found that GNRI was significantly lower in the OAB group versus the non-OAB group. GNRI significantly predicted OAB in a multifactorial logistic regression analysis. A nonlinear negative correlation was seen between GNRI and the risk for OAB in the elderly. GNRI outperformed serum albumin or body mass index alone in predicting OAB risk in a receiver operating characteristic analysis. The relationship between GNRI and OAB was mediated by inflammatory response, while a relatively weaker influence on the strength of the association between GNRI and OAB was seen for cognitive function.
"From a clinical perspective, GNRI can be incorporated into routine screening to enhance risk stratification and inform personalized treatment strategies, potentially improving outcomes for OAB patients or those at risk of OAB," the authors write
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted April 2025
Read this next
CDC, FDA Warn of Possible Salmonella Risk From Frozen Sprouted Beans
FRIDAY, July 18, 2025 -- The U.S. Centers for Disease Control and Prevention and the U.S. Food and Drug Administration, along with public health officials in several states, are...
Healthy Plant-Based Diet May Lower Inflammatory Bowel Disease Risk
WEDNESDAY, July 16, 2025 -- A healthy plant-based diet may reduce the risk for inflammatory bowel disease (IBD) due to the anti-inflammatory properties of the diet, according to a...
ENDO: Sweeteners, Genetic Predisposition Independently Linked to Early Puberty
TUESDAY, July 15, 2025 -- Sweetener consumption and genetic predisposition are independently associated with the risk for central precocious puberty (CPP), according to a study...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.