Skip to main content

Exposure to Glucocorticoids Increases Risk for New-Onset Diabetes

By Elana Gotkine HealthDay Reporter

Medically reviewed by Carmen Pope, BPharm. Last updated on Sep 12, 2024.

via HealthDay

WEDNESDAY, Sept. 11, 2024 -- Exposure to systemic glucocorticoids during hospitalization is associated with an increased risk for new-onset diabetes, according to a study presented at the annual of the European Association for the Study of Diabetes, held from Sept. 9 to 13 in Madrid.

Rajna Golubic, M.D., Ph.D., from the University of Oxford in the United Kingdom, and colleagues estimated the crude and age- and sex-adjusted incidence rate ratio (IRR) of new-onset diabetes arising during time exposed versus unexposed to systematic glucocorticoids. The analysis data set included 451,606 adults free from diabetes (median age, 52 years).

The researchers found that autoimmune/inflammatory diseases/infections were the most common indication for systemic glucocorticoids (65.3 percent). Overall, 1.8 and 0.8 percent of ever-exposed versus never-exposed individuals developed new-onset diabetes in the exposed and nonexposed time in years. The incidence rates were 51.9 and 18.5 per 100 person-years for the ever-exposed and never-exposed groups, respectively. The median length of stay in days was three and one for ever-exposed and never-exposed participants. For new-onset diabetes associated with glucocorticoids, the unadjusted and age- and sex-adjusted IRRs were 2.8 and 2.6, respectively.

"These latest results give clinical staff a better estimate of how likely new diabetes is to occur and could prompt doctors to plan clinical care more effectively to detect and manage new diabetes," Golubic said in a statement.

Abstract

More Information

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Read this next

New Subtype of Diabetes Identified in Sub-Saharan Africans, Black Americans

FRIDAY, Aug. 1, 2025 -- A new diabetes subtype has been identified in Sub-Saharan Africans and Black Americans, according to a study published online July 21 in The Lancet...

Three Healthy Dietary Patterns Lower Incidence of Type 2 Diabetes Across Ethnicities

THURSDAY, July 31, 2025 -- Three of the most widely studied healthy dietary patterns are associated with lower incidence of type 2 diabetes (T2D), regardless of an individual's...

Prediabetes Risk Doubled for Asian, Pacific Islander Teens With Overweight, Obesity

TUESDAY, July 29, 2025 -- Among adolescents with overweight or obesity, prediabetes is more than twice as common in Asian and Pacific Islander (Asian/PI) adolescents than in White...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.