Epilepsy Surgery for Neuroglial Tumors Shows Good Long-Term Outcomes
By Lori Solomon HealthDay Reporter
MONDAY, June 17, 2024 -- Patients with neuroglial tumors are ideal epilepsy surgical candidates, with good long-term outcomes observed, according to a study published online May 22 in Frontiers in Neurology.
Attila Rácz, M.D., Ph.D., from the University Hospital Bonn in Germany, and colleagues evaluated long-term outcomes and potential influencing factors among 107 patients who underwent surgery for neuroglial tumors (2001 to 2020) at a single institution.
The researchers found that 75 percent of the patients who underwent surgery achieved complete freedom from seizures at 12 months and 56 percent achieved complete freedom from seizures at the last follow-up visit (70.4 months; median: 40 months). For both 12-month follow-up outcomes and the longest available outcomes, completeness of resection was a crucial factor, while there was no consistent impact on postsurgical outcomes for lobar tumor localization, histology (ganglioglioma versus dysembryoplastic neuroepithelial tumor), history of bilateral tonic-clonic seizures prior to surgery, invasive diagnostics, side of surgery (dominant versus nondominant hemisphere), age at epilepsy onset, age at surgery, or epilepsy duration. Patients who underwent lesionectomy and lesionectomy with hippocampal resection showed similar outcomes.
"Neuroglial tumors present as excellent surgical substrates in treating structural epilepsy," the authors write. "To achieve an optimal postsurgical outcome, a complete lesion resection should be pursued whenever possible."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted June 2024
Read this next
New Definition of Epilepsy Improves Diagnosis, Treatment
TUESDAY, April 15, 2025 -- The new International League Against Epilepsy (ILAE) definition of epilepsy results in a higher frequency of epilepsy diagnosis and treatment, according...
Medial Temporal Lobectomy Aids Seizure Outcomes in Epilepsy
MONDAY, April 14, 2025 -- Medial temporal lobectomy is effective in improving seizure outcomes among patients with drug-resistant temporal lobe epilepsy, according to a study...
Updated AAN Position Statement Issued on Seizures, Driving Licensure
FRIDAY, March 28, 2025 -- In a position statement issued by the American Academy of Neurology and published online March 12 in Neurology, an updated consensus is presented...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.