CORSWO Model Stratifies Women According to Coronary Risk
By Elana Gotkine HealthDay Reporter
FRIDAY, Dec. 13, 2024 -- The Coronary Risk Score in Women (CORSWO) can predict the risk of major adverse cardiovascular events (MACE), according to a study published online Dec. 5 in Radiology: Cardiothoracic Imaging.
Guillermo Romero-Farina, M.D., Ph.D., from Vall d'Hebron University Hospital in Barcelona, Spain, and colleagues conducted a retrospective analysis including 2,226 women from a cohort of 25,943 consecutive patients referred for clinical gated single-photon emission computed tomography myocardial perfusion imaging. The occurrence of MACE was assessed during a mean follow-up of 4 ± 2.7 years.
The researchers found that 148 of 1,460 women in the training group had MACE (2.6 percent per year). The best model to predict MACE in women had an area under the receiver operating characteristic curve (AUC) of 0.80 and included age older than 69 years, diabetes mellitus, pharmacologic test, ST-segment depression (≥1 mm), myocardial ischemia >5 percent, perfusion defect at rest >9 percent, perfusion defect at stress >6 percent, and end-systolic volume index >15 mL. The model achieved moderate performance during validation in 766 women (AUC, 0.78). CORSWO allowed for stratification into four risk levels: low, moderate, high, and very high. In women, the high and very-high risk levels predicted MACE, with excellent performance (AUC, 0.78).
"CORSWO is an effective tool to stratify the risk for MACE into four risk levels, including high and very-high risk, with good accuracy, although requiring multiple imaging variables," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted December 2024
Read this next
CRC as First of Multiple Primary Malignancies Tied to Better Outcomes Than CRC as Only Malignancy
THURSDAY, June 26, 2025 -- Compared with colorectal cancer (CRC) presenting as an isolated primary or second primary malignancy, CRC presenting as the first of multiple primary...
Two-Hour Observation Probably Safe for Most Children With Anaphylaxis
THURSDAY, June 26, 2025 -- For most children who present to an emergency department with an acute allergic reaction requiring epinephrine, a two-hour observation period is...
CT Perfusion and CT Angiography Not Useful as Standalone Tests for Establishing Death by Neurologic Criteria
THURDAY, June 26, 2025 -- Neither computed tomography (CT) perfusion nor CT angiography meet the prespecified validation threshold as an ancillary test for death by neurologic...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.