Alcohol-Induced Liver Disease Hospitalizations, Transplants on the Rise
THURSDAY, Nov. 21, 2024 -- From 2005 to 2021, alcohol-induced liver disease (AILD)-related hospitalizations and liver transplants (LTs) increased among women and men and in younger and older adults, according to a research letter published online Nov. 14 in the Journal of the American Medical Association.
Vrishketan Sethi, M.D., from the University of Pittsburgh Medical Center, and colleagues examined trends in hospitalizations and LTs associated with AILD in the United States from 2005 to 2021. The patient population was stratified into younger and older groups (younger than 40 years and 40 years and older), excluding those younger than 20 years.
The researchers found that per 100,000 individuals, the rates of AILD-related hospitalizations increased from 63.47 to 129.24 in women, from 186.84 to 301.72 in men, from 33.89 to 102.27 among younger patients, and from 177.93 to 273.48 among older patients, respectively, from 2005 to 2021. The greatest relative increases and mean annual percentage change (MAPC) were seen among younger women and younger men (relative increases, 283.21 and 169.07 percent, respectively; MAPCs, 8.93 and 6.34, respectively). Per 1 million people, the rates of AILD-related LT increased from 1.88 to 8.39, from 10.36 to 20.09, from 0.70 to 7.27, and from 9.23 to 17.78 among women, men, younger adults, and older adults, respectively, from 2005 to 2021. The highest relative increases and MAPCs occurred among younger women and younger men (relative increases, 2,283.96 and 683.54 percent, respectively; MAPCs, 19.71 and 14.84, respectively).
"These findings highlight an important need to elucidate the biopsychosocial factors driving alcohol use and formulate preventive strategies targeted to younger individuals, especially females," the authors write.
One author disclosed ties to the pharmaceutical industry.
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Read this next
Alcohol Use Linked to Increased Dementia Risk
FRIDAY, Sept. 26, 2025 -- Alcohol use is associated with increased dementia risk, according to a study published online Sept. 23 in BMJ Evidence-Based Medicine. Anya Topiwala...
Alcohol-Induced Deaths Almost DoubledFrom 1999 to 2024
WEDNESDAY, Sept. 17, 2025 -- Rates of alcohol-induced deaths among U.S. adults nearly doubled from 1999 to 2024, according to a study published online Sept. 17 in PLOS Global...
Parental Diseases of Despair Linked to Suicidal Events in Offspring
MONDAY, Sept. 15, 2025 -- Parental diseases of despair (DoD; i.e., substance use disorder, alcohol-related disease, or suicidal behavior) are associated with suicidal events (SE)...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.