2016 to 2020 Did Not See Any Improvement in Takotsubo Cardiomyopathy Outcomes
By Lori Solomon HealthDay Reporter
FRIDAY, May 16, 2025 -- Takotsubo cardiomyopathy is associated with high mortality and complications, and recent years have seen little to no improvement in outcomes, according to a study published online May 14 in the Journal of the American Heart Association.
Mohammad Reza Movahed, M.D., Ph.D., from the University of Arizona Sarver Heart Center in Tucson, and colleagues evaluated outcomes for patients with Takotsubo cardiomyopathy. The analysis included data from 199,890 patients with Takotsubo identified through the Nationwide Inpatient Sample (2016 to 2020).
The researchers found that 83 percent of identified patients were female. Higher prevalence was also seen with age, White race, and highest income. Mortality was 6.5 percent, with no significant improvement noted during the study period. Men had doubled mortality compared with women (11.2 versus 5.5 percent). Major complications were substantial, including cardiogenic shock (6.6 percent), atrial fibrillation (20.7 percent), cardiac arrest (3.4 percent), congestive heart failure (35.9 percent), and stroke (5.3 percent).
"Takotsubo cardiomyopathy is a serious condition with a substantial risk of death and severe complications," Movahed said in a statement. "The health care team needs to carefully review coronary angiograms that show no significant coronary disease with classic appearance of left ventricular motion, suggesting any subtypes of stress-induced cardiomyopathy. These patients should be monitored for serious complications and treated promptly."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted May 2025
Read this next
CRC as First of Multiple Primary Malignancies Tied to Better Outcomes Than CRC as Only Malignancy
THURSDAY, June 26, 2025 -- Compared with colorectal cancer (CRC) presenting as an isolated primary or second primary malignancy, CRC presenting as the first of multiple primary...
Two-Hour Observation Probably Safe for Most Children With Anaphylaxis
THURSDAY, June 26, 2025 -- For most children who present to an emergency department with an acute allergic reaction requiring epinephrine, a two-hour observation period is...
CT Perfusion and CT Angiography Not Useful as Standalone Tests for Establishing Death by Neurologic Criteria
THURDAY, June 26, 2025 -- Neither computed tomography (CT) perfusion nor CT angiography meet the prespecified validation threshold as an ancillary test for death by neurologic...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.