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2005 to 2019 Saw Increase in Incidence of Cervical Artery Dissection

Medically reviewed by Carmen Pope, BPharm. Last updated on April 4, 2025.

By Elana Gotkine HealthDay Reporter

FRIDAY, April 4, 2025 -- Cervical artery dissection (CeAD) incidence increased from 2005 to 2019, with the increase in admissions particularly high in older, Black, and Hispanic populations, according to a study published online April 2 in Neurology.

Liqi Shu, M.D., from The Warren Alpert Medical School of Brown University in Providence, Rhode Island, and colleagues determined national trends in CeAD admissions and examined post-CeAD risk for ischemic stroke using data from the National Inpatient Sample (2005 to 2019), National Readmission Database (2015 to 2019), and State Inpatient Database for New York (2011 to 2017) and Florida (2011 to 2019).

A total of 125,102 patients with spontaneous CeAD were identified from 2005 to 2019. The researchers observed an increase in CeAD incidence from 10.7 to 45.6 cases per million population from 2005 to 2019, with an average annual percent change (AAPC) of 10.21 percent. In the older, Black, and Hispanic populations, this increase in CeAD admissions was particularly high. The upward trend was corroborated in statewide data, with an AAPC of 8.47 percent. Vertebral artery dissection was the sole major predictor of subsequent ischemic stroke risk within 90 days among patients with CeAD without acute ischemic stroke (adjusted subdistributed hazard ratio, 1.77). Similar results were seen in interaction and subgroup analyses.

"Our data highlight the importance of increased clinical vigilance to avert recurrent stroke, and future research should target the most efficacious treatment modalities for vertebral artery dissection," the authors write.

Several authors disclosed ties to the biopharmaceutical and medical device industries.

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Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

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