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iPlex Insmed Incorporated - Treatment for Severe Primary IGF-1 Deficiency

iPlex, mecasermin rinfabate, is the human recombinant of the naturally occurring protein complex of insulin-like growth factor-I (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3). iPlex is indicated for the treatment of growth failure in children with severe primary IGF-1 deficiency (Primary IGFD) or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH.

Posted: December 2005

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iPlex (mecasermin rinfabate [rDNA origin]) FDA Approval History