Generic name: olezarsen ( )
Drug class: Miscellaneous antihyperlipidemic agents

Medically reviewed by Drugs.com on Feb 3, 2025. Written by Cerner Multum.

What is Tryngolza Autoinjector?

Tryngolza Autoinjector is used together with a low-fat diet to reduce triglycerides (a type of fat in the blood) in adults with familial chylomicronemia syndrome (a condition that prevents the body from breaking down fats).

Tryngolza Autoinjector may also be used for purposes not listed in this medication guide.

Tryngolza Autoinjector side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Tryngolza Autoinjector may cause serious side effects. Stop using Tryngolza Autoinjector and call your doctor at once if you have:

• bronchospasm (wheezing, chest tightness, trouble breathing);

• chills, muscle pain;

• severe itching; or

• skin redness or a rash that spreads.

Common side effects of Tryngolza Autoinjector may include:

• pain, redness, bruising, swelling, or irritation where the medicine was injected;

• low levels of platelets in your blood; or

• joint pain or stiffness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use Tryngolza Autoinjector if you are allergic to it.

It is not known if Tryngolza Autoinjector will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using Tryngolza Autoinjector.

How should I use Tryngolza Autoinjector?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Tryngolza Autoinjector is injected under the skin, usually once a month. A healthcare provider will show you where to inject this medicine.

Ask your doctor or pharmacist if you don't understand how to use an injection.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.

Throw away the autoinjector after one use, even if there is still medicine left inside.

Your treatment may also include diet, exercise, weight control, and blood tests. Follow your doctor's instructions very closely.

Store this medicine in the original container in the refrigerator. Protect from light and do not freeze or shake the medicine.

Take the medicine out of the refrigerator and let it reach room temperature before using.

Do not warm the medicine with hot water, sunlight, or a microwave.

You may store this medicine at room temperature for up to 6 weeks. Throw the medicine away if not used within 6 weeks. Do not put it back into the refrigerator. Protect from heat.

What happens if I miss a dose?

Use the medicine as soon as you remember, and then go back to your regular schedule. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Tryngolza Autoinjector?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Tryngolza Autoinjector?

Other drugs may affect Tryngolza Autoinjector, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2025 Cerner Multum, Inc. Version: 1.01.