Revakinagene taroretcel ophthalmic

Generic name: revakinagene taroretcel ophthalmic
Brand name: Encelto
Dosage form: intravitreal implant (lwey)
Drug class: Miscellaneous uncategorized agents

Medically reviewed by Drugs.com on Jun 23, 2025. Written by Cerner Multum.

What is revakinagene taroretcel ophthalmic?

Revakinagene taroretcel is used to treat adults with an eye condition called idiopathic macular telangiectasia type 2.

Revakinagene taroretcel ophthalmic may also be used for purposes not listed in this medication guide.

Revakinagene taroretcel ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Revakinagene taroretcel may cause some side effects following the procedure. Call your doctor at once if you have: worsening eye swelling, redness, severe discomfort, crusting, discharge, a cloudy or hazy appearance over your eye or in your vision, seeing halos around lights, seeing flashes of light, vision loss, bleeding inside your eye, increased sensitivity to light, irritation, or other surgical complications such as discomfort due to the implant moving out of place (implant extrusion).

Common side effects of revakinagene taroretcel ophthalmic may include:

• eye pain, redness, discharge, dryness, itching or irritation;

• feeling like something is in your eye;

• trouble seeing in the dark;

• seeing "floaters" in your vision; or

• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not receive revakinagene taroretcel if you are allergic to Endothelial Serum Free Media (Endo-SFM), or if you have:

• an active or suspected infection in or around your eye.

Tell your doctor if you have any active or suspected infection.

It is not known if revakinagene taroretcel will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed after using revakinagene taroretcel ophthalmic.

How is revakinagene taroretcel ophthalmic given?

Revakinagene taroretcel is given as an implant into your eye. The procedure will be performed in your ophthalmologist's (eye doctor) office or other clinic setting.

Your doctor will make sure revakinagene taroretcel is the right treatment for you.

You will receive a Patient card about your eye implant. Show this card to your imaging technician if you need Magnetic Resonance Imaging (MRI) for important safety information. Keep the card with you at all times.

Make sure to not miss any follow-up appointments with your doctor.

Tell the doctor ahead of time that you have a revakinagene taroretcel implant before any vision exam.

You may be given other medications to help prevent serious side effects or infection after the procedure. Keep taking these medicines for as long as your doctor has prescribed.

You may have problems seeing when moving from a bright to a dark environment. Consider using flashlights or nightlights at home. Wear protective eyewear (like sunglasses) during the day and use an eye shield at night for one week after the procedure.

Revakinagene taroretcel ophthalmic dosing information

Usual Adult Dose for Macular Telangiectasia:

1 implant per affected eye

Comments:
-Each implant contains 200,000 to 440,000 allogeneic retinal pigment epithelial cells expressing recombinant 129 human ciliary neurotropic factor, a neurotrophic factor.

Use: For the treatment of patients with idiopathic macular telangiectasia type 2

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your revakinagene taroretcel implant.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid after receiving revakinagene taroretcel ophthalmic?

Avoid water in your eyes and lifting anything heavy (over 20 pounds) for one week after the eye procedure.

revakinagene taroretcel ophthalmic may cause blurred vision. Avoid driving, hazardous activity, or walking in the dark until the eye shield has been removed and your doctor informs you that your vision has recovered.

What other drugs will affect revakinagene taroretcel ophthalmic?

Tell your doctor about all your other medicines, especially:

• if you use a blood thinner (such as warfarin) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, naproxen.

Other drugs may affect revakinagene taroretcel ophthalmic, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Revakinagene taroretcel Biosimilars

Biosimilar and interchangeable products are biological products that are highly similar to and have no clinically meaningful differences from the reference product.

Reference products

These are biological products that have already been approved by the FDA, against which biosimilar products are compared. There is 1 for revakinagene taroretcel.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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