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Betadine Douche

Generic name: povidone iodine vaginalPO-vi-done-EYE-oh-dine-VAG-in-al ]
Brand names: Summers Eve, Betadine Douche, Massengill Medicated Douche
Drug classes: Antiseptic and germicides, Vaginal anti-infectives

Medically reviewed by on Aug 3, 2023. Written by Cerner Multum.

What is Betadine Douche?

There are many brands and forms of povidone iodine vaginal available. Not all brands are listed on this leaflet.

Betadine Douche is used to provide temporary relief from minor vaginal irritation, soreness, or itching.

Betadine Douche should not be used to prevent pregnancy or sexually transmitted disease.

Betadine Douche may also be used for purposes not listed in this medication guide.

Betadine Douche side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Betadine Douche may cause serious side effects. Stop using Betadine Douche and call your doctor at once if you have:

  • ongoing vaginal pain or soreness;

  • itching, swelling, or redness;

  • vaginal dryness; or

  • severe irritation or burning.

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Use exactly as directed on the label, or as prescribed by your doctor.

Before taking this medicine

You should not use Betadine Douche if you are allergic to it.

Ask a doctor or pharmacist if Betadine Douche is safe to use if you have:

  • kidney disease; or

  • a thyroid disorder.

Ask a doctor before using this medicine if you are pregnant.

Do not use this medicine in a child or teenager without medical advice.

How should I use Betadine Douche?

Use exactly as directed on the label, or as prescribed by your doctor.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Do not take by mouth. This medicine is for use only in the vagina.

Gently insert the applicator nozzle no more than 3 inches into your vagina. Squeeze the bottle slowly, while allowing the liquid to flow freely out of the vagina. Use this medicine while sitting on the toilet or standing in a tub or shower.

When treating an infection, you may be given antibiotic or antifungal medicine to take by mouth or use in the vagina. Use all medicines for the full prescribed length of time, even if your symptoms quickly improve.

You should not use Betadine Douche for longer than 7 days without medical advice. Follow all directions on the medicine label.

Call your doctor if you have new or worsening symptoms such as pelvic pain, fever, chills, nausea, vomiting, yellow or foul-smelling vaginal discharge, painful and frequent urination, or genital sores.

Betadine Douche can stain skin and fabrics. You may use rubbing alcohol to remove staining from your skin. Stains on fabric can be removed by rinsing with ammonia diluted with water. Avoid getting the medicine on jewelry, especially silver.

Store at room temperature away from moisture and heat.

Each Betadine Douche disposable douche is for one use only.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

An overdose of Betadine Douche is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medicine.

What should I avoid while using povidone iodine vaginal?

Do not get Betadine Douche in your eyes. If contact does occur, rinse with water. Seek medical advice if you have ongoing eye irritation.

Avoid using other vaginal products or medications unless your doctor tells you to.

What other drugs will affect Betadine Douche?

Medicine used in the vagina is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.